Evidence map›Paper›PMID 35515960›Full record

ArticleSisli Etfal Hastanesi tip bulteni2022

Lymphocyte to Monocyte Ratio and C-Reactive Protein Combination as the Best Simple Predictor of Treatment Response in Cirrhotic Patients with Culture Negative Neutrocytic Ascites.

Sezgin Barutcu, Abdullah Emre Yildirim, Ahmet Sahin, Murat Taner Gulsen

Abstract read
In one paragraph

Article in Sisli Etfal Hastanesi tip bulteni, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sezgin BarutcuDivision of Gastroenterology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.ORCID https://orcid.org/0000-0003-0823-3215
Abdullah Emre YildirimDivision of Gastroenterology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.ORCID https://orcid.org/0000-0002-4386-9297
Ahmet SahinDepartment of Infectious Disease and Clinical Microbiology, University of Health Sciences Turkey, Mehmet Akif Inan Research and Training Hospital, Şanlıurfa, Turkey.ORCID https://orcid.org/0000-0002-8377-8293
Murat Taner GulsenDepartment of Infectious Disease and Clinical Microbiology, University of Health Sciences Turkey, Mehmet Akif Inan Research and Training Hospital, Şanlıurfa, Turkey.ORCID https://orcid.org/0000-0002-8531-9402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to evaluate the most ideal inflammatory markers for treatment response and to determine a cutoff value that could predict response to treatment for culture negative neutrocytic ascite (CNNA) patients. Methods: This is a retrospective cross-sectional case-controlled study. Patients with CNNA were evaluated by taking ascites fluid sampling at the beginning and on the 5 Results: Of the 123 cases with cirrhotic ascites disease, 59 were CCNA and 64 were the control group without ascite-fluid infection. There were statistically significant differences for blood monocyte count, NLR (p<0.01), LMR, and C-reactive protein (CRP) (p<0.001) between two groups. Patients in the CNNA group were compared before and after treatment among themselves for the treatment response. There was statistically significant difference in mean platelet volume, monocyte, LMR, and CRP (p<0.05) between two groups. After receiver operator characteristics curve analysis, the best cutoff value for monocyte was <0.64 × 10 Conclusion: Our results showed that in cirrhotic patients with CNNA, combined LMR + CRP can be used as a novel, low cost and non-invasive test to predict treatment response.

Indexed as

Ascitic fluid infectioncirrhosisc-reactive proteinculture negative neutrocytic asciteslymphocyte to monocyte ratio

Identifiers

PMID35515960
PMCPMC9040302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.