Evidence map›Paper›PMID 35515921›Full record

ArticleRSC advances2019

pDobz/pDobb protected diaminodiacid as a novel building block for peptide disulfide-bond mimic synthesis.

Chao Liu, Yan Zou, Honggang Hu, Yunyun Jiang, Luping Qin

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Chao LiuCollege of Pharmacy, Second Military Medical University Shanghai China.ORCID https://orcid.org/0000-0001-9176-7343
Yan ZouCollege of Pharmacy, Second Military Medical University Shanghai China.ORCID https://orcid.org/0000-0002-0274-7365
Honggang HuCollege of Pharmacy, Second Military Medical University Shanghai China.
Yunyun JiangDepartment of Pharmacy No. 101 Hospital of PLA Wuxi China Shygm98@163.com.
Luping QinCollege of Pharmacy, Second Military Medical University Shanghai China.
Second Military Medical University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diaminodiacid strategy has been widely studied in the chemical synthesis of peptide disulfide bond mimics. Diaminodiacid building blocks, which are key intermediates, are currently under the spotlight. However, one technical bottleneck inherent in existing building blocks is the contamination problem caused by the heavy metal reagents during the deprotection process, which makes the peptides less suitable for pharmaceutical use. Herein, we describe the successful development of a

Identifiers

PMID35515921
PMCPMC9060753
OpenAlexW2912852735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.