Evidence map›Paper›PMID 35515841›Full record

ArticleRSC advances2019

Insight into the DNA adsorption on nitrogen-doped positive carbon dots.

Fenglan Li, Qianqian Cai, Xiaoli Hao, Chengfei Zhao, Zhengjun Huang, Yanjie Zheng, Xinhua Lin, Shaohuang Weng

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Carbon Dots: An Innovative Tool for Drug Delivery in Brain Tumors.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fenglan LiDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Qianqian CaiDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Xiaoli HaoDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Chengfei ZhaoDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Zhengjun HuangDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Yanjie ZhengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Xinhua LinDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.
Shaohuang WengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University Fuzhou 350122 China shweng@fjmu.edu.cn gillzheng@163.com xhl1963@sina.com.ORCID https://orcid.org/0000-0002-4739-5615
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considerable biosensors have been fabricated on the basis of DNA interaction with carbon nanomaterials, such as graphene oxide (GO) nanosheets. Few studies have focused on the rational design of sensors between carbon dots (CDs) and DNA due to the limited understanding of the real forces behind the adsorption of DNA on CDs. In this work, nitrogen doping-positive CDs (N-CDs), which can quench fluorophore-labeled DNA, were investigated to ascertain the interaction between the CDs and DNA. With reference to DNA adsorption on GO, the adsorption capacity and kinetics of N-CDs for DNA were studied. Desorption of DNA from these surfaces was also measured. Moreover, DNA desorption and anchoring force of N-CDs to DNA were different from those of GO, given that the prepared N-CDs and GO were positively and negatively charged, respectively. Accordingly, DNA was adsorbed on N-CDs mainly

Identifiers

PMID35515841
PMCPMC9063714
OpenAlexW2941908363

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.