Evidence map›Paper›PMID 35515703›Full record

ArticleAdvances in redox research2022

Vitamin B12 does not increase cell viability after hydrogen peroxide induced damage in mouse kidney proximal tubular cells and brain endothelial cells.

Azraa Ayesha, Edward M Bahnson, Yukako Kayashima, Jennifer Wilder, Phillip K Huynh, Sylvia Hiller, Nobuyo Maeda-Smithies, Feng Li

Open access · goldAbstract read
In one paragraph

Article in Advances in redox research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Vitamin BAnimals : an open access journal from MDPI · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Azraa AyeshaDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
Edward M BahnsonDepartment of Cell Biology and Physiology, The University of North Carolina, Chapel Hill, NC 27599, USA.
Yukako KayashimaDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
Jennifer WilderDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
Phillip K HuynhHackensack Meridian School of Medicine, Nutley, NJ 07110, USA.
Sylvia HillerDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
Nobuyo Maeda-SmithiesDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
Feng LiDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 703 Brinkhous-Bullitt Bldg, CB # 7525, Chapel Hill, NC 27599, USA.
University of North Carolina at Chapel Hill · USCenter for Discovery · US

Funding

MODELS FOR STUDYING THE GENETICS OF HYPERTENSIONR01HL049277 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAEDA, NOBUYO · 1992 to 2025
$17.5M
Benefits of nicotinamide in placental development and in preeclamsiaR01HD101485 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LI, FENG · 2021 to 2025
$2.1M
Cell-Mediated Targeted Redox Intervention for the Treatment and Prevention of AtherosclerosisK01HL145354 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BAHNSON, EDWARD M · 2020 to 2023
$528k
NHLBI NIH HHS K01 HL145354NHLBI NIH HHS R01 HL049277NICHD NIH HHS R01 HD101485
6 · The paper itself

Abstract

Vitamin B12 (B12) is an essential co-factor for two enzymes in mammalian metabolism and can also act as a mimetic of superoxide dismutase (SOD) converting superoxide (O

Indexed as

bEdn.3 cellsBU.MPT cellsCell viabilityHydrogen peroxideVitamin B12

Identifiers

PMID35515703
PMCPMC9067605
OpenAlexW4205851512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.