ArticleRSC advances2019
Novel polymeric derivatives of betulin with anticancer activity.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Drug Delivery Systems of Betulin and Its Derivatives: An Overview.Biomedicines · 2024Review
- New Biodegradable Copolymers Based on Betulin and Hydroxycarboxylic Acid Derivatives.Materials (Basel, Switzerland) · 2024Article
- Antiproliferative and Cytotoxic Properties of Propynoyl Betulin Derivatives against Human Ovarian Cancer Cells: In Vitro Studies.International journal of molecular sciences · 2023Article
- Polyanhydride Chemistry.Biomacromolecules · 2022Review
- Highly Branched Betulin Based Polyanhydrides for Self-Assembled Micellar Nanoparticles Formulation.International journal of molecular sciences · 2022Article
- Antioxidant Activity of New Copolymer Conjugates of Methoxyoligo(Ethylene Glycol)Methacrylate and Betulin Methacrylate with Cerium Oxide NanoparticlesMolecules (Basel, Switzerland) · 2022Article
- Synthesis of Aliphatic Polyanhydrides with Controllable and Reproducible Molecular Weight.Pharmaceutics · 2022Article
- Biodegradable and Bioactive Carriers Based on Poly(betulin disuccinate-Pharmaceutics · 2022Article
- Enhancement of the Antioxidant and Skin Permeation Properties of Betulin and Its Derivatives.Molecules (Basel, Switzerland) · 2021Article
- Bioactive Betulin and PEG Based Polyanhydrides for Use in Drug Delivery Systems.International journal of molecular sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to provide novel polymeric biomaterials for chemotherapeutic purposes, in this paper we described the synthesis and the characterization of the physicochemical properties of a betulin-based polyanhydride exhibiting anti-cancer effects. The polyanhydride was obtained by a melt polycondensation of a disuccinate betulin (3,28-di-
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.