Evidence map›Paper›PMID 35515333›Full record

ArticleRSC advances2019

Down-regulation of MRPS23 inhibits LPS-induced proliferation and invasion

Ai-Guo Liu, Ke-Lin Xu, Wei-Lin Wang, Bing-Kang Zhou, Qing-Gong Guo

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ai-Guo LiuDepartment of Orthopaedics, The First Affiliated Hospital of Henan University Kaifeng 475000 China.
Ke-Lin XuDepartment of Orthopaedics and Traumatology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine No. 8 Zhongnan West Road Wuxi 214000 China xukelin_orth@163.com +86-510-88859999 +86-510-88859999.ORCID https://orcid.org/0000-0003-1665-6015
Wei-Lin WangDepartment of Orthopaedics, The First Affiliated Hospital of Henan University Kaifeng 475000 China.
Bing-Kang ZhouDepartment of Orthopaedics, The First Affiliated Hospital of Henan University Kaifeng 475000 China.
Qing-Gong GuoDepartment of Orthopaedics, The First Affiliated Hospital of Henan University Kaifeng 475000 China.
Kaifeng University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial ribosomal protein S23 (MRPS23), encoded by a nuclear gene, is a participant in the translation of mitochondrial proteins. Recently, MRPS23 has been reported to be overexpressed in many types of cancers and have a close association with cancer progression. However, the specific roles of MRPS23 in osteosarcoma (OS) remain unknown. In this study, we investigated the expression pattern and biological functions of MRPS23 in OS cells. Our results demonstrated that MRPS23 was up-regulated in OS tissues and cell lines. Down-regulation of MRPS23 significantly inhibited OS cell proliferation and invasion induced by lipopolysaccharide (LPS)

Identifiers

PMID35515333
PMCPMC9062464
OpenAlexW2929087275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.