Evidence map›Paper›PMID 35514936›Full record

ArticleRSC advances2020

Synthesis of novel naphthalene-heterocycle hybrids with potent antitumor, anti-inflammatory and antituberculosis activities.

Mohamed Ahmed Abozeid, Aya Atef El-Sawi, Mohamed Abdelmoteleb, Hanem Awad, Marwa Mostafa Abdel-Aziz, Abdel-Rahman Hassan Abdel-Rahman, El-Sayed Ibrahim El-Desoky

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed Ahmed AbozeidDepartment of Chemistry, Faculty of Science, Mansoura University Mansoura-35516 Egypt prof.deosky.orgchem@gmail.com desoky199@mans.edu.eg +201060614054.ORCID https://orcid.org/0000-0001-5191-4492
Aya Atef El-SawiDepartment of Chemistry, Faculty of Science, Mansoura University Mansoura-35516 Egypt prof.deosky.orgchem@gmail.com desoky199@mans.edu.eg +201060614054.
Mohamed AbdelmotelebFood Allergy Research & Resource Program (FARRP), Department of Food Science & Technology, University of Nebraska Lincoln NE USA.ORCID https://orcid.org/0000-0001-9453-3219
Hanem AwadDepartment of Tanning Materials and Leather Technology, Chemical Industries Research Division, National Research Centre 33 EL-Bohouth St., Dokki 12622 Giza Egypt.ORCID https://orcid.org/0000-0002-3970-2371
Marwa Mostafa Abdel-AzizThe Regional Center for Mycology and Biotechnology, Al-Azhar University Cairo 11759 Egypt.
Abdel-Rahman Hassan Abdel-RahmanDepartment of Chemistry, Faculty of Science, Mansoura University Mansoura-35516 Egypt prof.deosky.orgchem@gmail.com desoky199@mans.edu.eg +201060614054.
El-Sayed Ibrahim El-DesokyDepartment of Chemistry, Faculty of Science, Mansoura University Mansoura-35516 Egypt prof.deosky.orgchem@gmail.com desoky199@mans.edu.eg +201060614054.ORCID https://orcid.org/0000-0003-1621-9296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multitarget-directed drugs (hybrid drugs) constitute an efficient avenue for the treatment of multifactorial diseases. In this work, novel naphthalene hybrids with different heterocyclic scaffolds such as nicotinonitrile, pyran, pyranopyrazole, pyrazole, pyrazolopyridine, and azepine were efficiently synthesized

Identifiers

PMID35514936
PMCPMC9058152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.