Evidence map›Paper›PMID 35514877›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Prognosis of patients with active cancer undergoing transcatheter aortic valve implantation: An insight from Japanese multicenter registry.

Yoshimasa Kojima, Ryosuke Higuchi, Kenichi Hagiya, Mike Saji, Itaru Takamisawa, Nobuo Iguchi, Shuichiro Takanashi, Shinichiro Doi, Shinya Okazaki, Kei Sato and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2024
    Article
  4. Article
  5. Article
  6. Defining high bleeding risk in patients undergoing transcatheter aortic valve implantation: a VARC-HBR consensus document.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Yoshimasa KojimaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Ryosuke HiguchiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Kenichi HagiyaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Mike SajiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Itaru TakamisawaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Nobuo IguchiDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Shuichiro TakanashiDepartment of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.
Shinichiro DoiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shinya OkazakiDepartment of Cardiovascular Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kei SatoDepartment of Cardiology, Mie University Hospital, Mie, Japan.
Harutoshi TamuraDepartment of Cardiology, Pulmonology and Nephrology, Yamagata University Hospital, Yamagata, Japan.
Morimasa TakayamaDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Takanori IkedaDepartment of Cardiology, Toho University, Tokyo, Japan.
Mitsuaki IsobeDepartment of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
Sakakibara Hospital · JPJuntendo University · JPToho University · JPMie University Hospital · JPYamagata University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Malignancy is common in older adults undergoing transcatheter aortic valve implantation (TAVI), and may affect prognosis. The present study aimed to examine whether active cancer affects all-cause mortality rates among patients undergoing TAVI. Methods: This retrospective study examined data from 1,114 consecutive patients treated between April 2010 and June 2019. Patients with life expectancy of <1 year due to non-cardiac causes were excluded. Results: Active cancer was defined as cancer under treatment or cured within 1 year, and was recognized in 62 patients (5.6%) with (n = 17) and without (n = 45) metastases. In multivariate analysis, being female (hazard ratio [HR] 0.55, 95% confidence interval [CI] 0.39-0.77, p < 0.001), body mass index (BMI) (HR = 0.92 per 1 kg/m Conclusion: In patients undergoing TAVI, being female, high BMI, NYHA class III/IV, atrial fibrillation, albumin levels, and cancer metastasis were factors associated with mortality. Meanwhile, active cancer without metastasis was not associated with increased mortality rates. These findings would help clinical decision-making by patients and physicians.

Indexed as

AS, aortic stenosisCancerCarcinomaCI, confidence intervalCT, computed tomographyHR, hazard ratioMalignancyMortalityNYHA, New York Heart AssociationSAVR, surgical aortic valve replacementTAVI, transcatheter aortic valve implantationTranscatheter aortic valve replacement

Identifiers

PMID35514877
PMCPMC9066355
OpenAlexW4225264178

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.