ArticleRSC advances2019
A novel multi-reaction microdroplet platform for rapid radiochemistry optimization.
Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Scalable droplet-based radiosynthesis of [Lab on a chip · 2024Article
- Proof-of-concept optimization of a copper-mediatedLab on a chip · 2023Article
- Accelerating radiochemistry development: Automated robotic platform for performing up to 64 droplet radiochemical reactions in a morning.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2023Article
- A rapid and systematic approach for the optimization of radio thin-layer chromatography resolution.Journal of chromatography. A · 2023Article
- Article
- Optimization of Radiochemical Reactions using Droplet Arrays.Journal of visualized experiments : JoVE · 2021Article
- Cerenkov Luminescence Imaging in the Development and Production of Radiopharmaceuticals.Frontiers in physics · 2021Article
- A simple and efficient automated microvolume radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2020Article
- Green and efficient synthesis of the radiopharmaceutical [Reaction chemistry & engineering · 2020Article
- High-Efficiency Production of Radiopharmaceuticals via Droplet Radiochemistry: A Review of Recent Progress.Molecular imagingReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
During the development of novel tracers for positron emission tomography (PET), the optimization of the synthesis is hindered by practical limitations on the number of experiments that can be performed per day. Here we present a microliter droplet chip that contains multiple sites (4 or 16) to perform reactions simultaneously under the same or different conditions to accelerate radiosynthesis optimization.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.