Evidence map›Paper›PMID 35514623›Full record

ArticleRSC advances2019

A novel method for the highly efficient biotransformation of genistein from genistin using a high-speed counter-current chromatography bioreactor.

Daijie Wang, Muhammad Shafiq Khan, Li Cui, Xiangyun Song, Heng Zhu, Tianyu Ma, Xiaoyu Li, Rong Sun

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Cellular and Molecular Mechanisms Modulated by Genistein in Cancer.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Molecular Pathways of Genistein Activity in Breast Cancer Cells.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Daijie WangKey Laboratory of TCM Quality Control, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Jinan 250014 P. R. China.ORCID https://orcid.org/0000-0002-2156-4548
Muhammad Shafiq KhanDepartment of Biotechnology and Bioinfomatics, International Islamic University Islamabad 44000 Islamic Republic of Pakistan.
Li CuiKey Laboratory of TCM Quality Control, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Jinan 250014 P. R. China.
Xiangyun SongKey Laboratory of TCM Quality Control, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Jinan 250014 P. R. China.
Heng ZhuKey Laboratory of TCM Quality Control, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Jinan 250014 P. R. China.
Tianyu MaKey Laboratory of TCM Quality Control, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences) Jinan 250014 P. R. China.
Xiaoyu LiCollege of Pharmacy, Shandong University of Traditional Chinese Medicine Jinan China.
Rong SunInstitute of Advanced Medical Science, Shandong University Jinan 250012 P. R. China sunrong@sdu.edu.cn.
Qilu University of Technology · CNShandong University of Traditional Chinese Medicine · CNInternational Islamic University, Islamabad · PKShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genistein, an important soybean isoflavone compound, has gained attention for its significant properties. Compared with the glycone form of genistin, low content of genistein limits the use in food and pharmaceutical fields. In this study, a novel bioreactor with high-speed counter-current chromatography (HSCCC) was built for the highly efficient biotransformation of genistein from genistin. The solvent system for the bioreactor was selected according to the

Identifiers

PMID35514623
PMCPMC9060664
OpenAlexW2913112477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.