Evidence map›Paper›PMID 35514479›Full record

ArticleRSC advances2019

Chitosan/hydroxyapatite modified carbon/carbon composites: synthesis, characterization and

Wenbo Wang, Ning Cao, Jianwen Dong, Rabah Boukherroub, Wei Liu, Yujie Li, Haibo Cong

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Wenbo WangDepartment of Orthopaedics, The 8th Clinical College (Weihai Central Hospital), Qingdao University Qingdao Shandong Province 266021 P. R. China haibocong@163.com.
Ning CaoKey Laboratory of Unconventional Oil & Gas Development, China University of Petroleum (East China) Qingdao 266580 P. R. China.ORCID https://orcid.org/0000-0001-5110-9864
Jianwen DongDepartment of Orthopaedics, The Second Affiliated Hospital, Shandong University of Traditional Chinese Medicine Jinan Shandong Province 250001 P. R. China.
Rabah BoukherroubUniv. Lille, CNRS, Centrale Lille, ISEN, Univ. Valenciennes, UMR 8520, IEMN Lille France.
Wei LiuScientific Research Department of Shandong University of Traditional Chinese Medicine Jinan Shandong Province 250001 P. R. China.
Yujie LiDepartment of Geriatric Medicine, The Second Affiliated Hospital, Shandong University of Traditional Chinese Medicine Jinan Shandong Province 250001 P. R. China liyujie.11@163.com.ORCID https://orcid.org/0000-0002-6249-2237
Haibo CongDepartment of Orthopaedics, The 8th Clinical College (Weihai Central Hospital), Qingdao University Qingdao Shandong Province 266021 P. R. China haibocong@163.com.
Shandong University of Traditional Chinese Medicine · CNQingdao University · CNCentre National de la Recherche Scientifique · FRQingdao Center of Resource Chemistry and New Materials · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon/carbon composite (C/C), due to its bio-inert property, is prone to cause bone consolidation defects and bacterial infections in clinical applications. Therefore, there is a great demand in practical applications to prevent implant infections and enhance its bone consolidation capability. In this study, we have developed a facile approach to construct a chitosan/hydroxyapatite composite modified layer on C/C surface by electrochemical deposition and a covalent grafting technique, and the modified layer has both the antibacterial activity of chitosan (CS) and the bioactivity of hydroxyapatite (HAP). The microstructure and chemical composition of the modified layer were analyzed using scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) and water contact angle measurements. The biological properties of the composites were evaluated using cell culture, antimicrobial test and real-time quantitative PCR

Identifiers

PMID35514479
PMCPMC9067253
OpenAlexW2964504968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.