Evidence map›Paper›PMID 35514245›Full record

ArticleDrug testing and analysis2022

Stability of drugs of abuse in synthetic oral fluid investigated using a simple "dilute and inject" method of analysis.

Ivana Gavrilović, Alessandro Musenga, Kim Wolff, Alison Woffendin, Andrew Smart, Fan Gong, Duncan Harding, David Cowan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug testing and analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ivana GavrilovićDrug Control Centre, King's Forensics, King's College London, London.ORCID https://orcid.org/0000-0003-4942-6398
Alessandro MusengaDrug Control Centre, King's Forensics, King's College London, London.
Kim WolffDrug Control Centre, King's Forensics, King's College London, London.
Alison WoffendinDrug Control Centre, King's Forensics, King's College London, London.
Andrew SmartDrug Control Centre, King's Forensics, King's College London, London.
Fan GongHome Office, Centre for Applied Science and Technology (CAST), London, UK.
Duncan HardingHome Office, Centre for Applied Science and Technology (CAST), London, UK.
David CowanDepartment of Analytical, Environmental and Forensic Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0001-6407-1113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human oral fluid is well established as a matrix for drug screening, particularly in the workplace. The need to synthesise synthetic oral fluid (SOF) has been recognised in order to overcome human oral fluid's composition variability. We have used SOF spiked with six common drugs of abuse or their primary metabolites: morphine, amfetamine, benzoylecgonine, cocaine, diazepam, and (-)-Δ

Indexed as

CocaineSubstance Abuse DetectionAmphetamineChromatography, LiquidDiazepamDronabinolHumansMorphine DerivativesSalivaTandem Mass SpectrometryAmphetamineCocaineDiazepamDronabinolMorphine Derivatives“dilute and inject”drug stabilityLC-MS/MSsynthetic OF

Identifiers

PMID35514245
PMCPMC9543709

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.