Evidence map›Paper›PMID 35514242›Full record

ArticleEuropean journal of clinical investigation2022

'Obesities': Position statement on a complex disease entity with multifaceted drivers.

Patricia Yárnoz-Esquiroz, Laura Olazarán, Maite Aguas-Ayesa, Carolina M Perdomo, Marta García-Goñi, Camilo Silva, José Antonio Fernández-Formoso, Javier Escalada, Fabrizio Montecucco, Piero Portincasa and 1 more

3 registry-linked trialsAbstract readConsensus Statement
In one paragraph

Article in European journal of clinical investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05447351 unknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Personalized Dietary and Lifestyle Treatments on the Reduction of Cardiovascular and Metabolic Risk in Overweight and Obese Patients

Typeobservational_patient_registrySponsorUniversity of BariRan2023 to 2025Enrolled200ConditionsOverweight and Obesity, Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
NCT06226194 recruitingnot on this mapstarted 2024, after this paper: background citation

Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery

Typeobservational_patient_registrySponsorInstitut de Recerca Biomèdica de LleidaRan2024 to 2028Enrolled6,966ConditionsBariatric Surgery Candidate, Obesity, Morbid, Genetic Predisposition, Metabolic Syndrome
NCT07035704 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

De-Risking Metabolic, Environmental and Behavioral Determinants of Obesity in Children, Adolescents and Young Adults

TypeinterventionalSponsorpiero portincasaRan2025 to 2027Enrolled200ConditionsOverweight (BMI &gt, 25)ArmsMeD enriched with mushrooms, MeD enriched the Lebanese herbal mixture Za'atar, MeD Diet + semaglutinine or compatible treatment+ Za'atar or Mushroom (to be defined)
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Time to Address Eating Disorder Risk Among Medical Students.Behavioral sciences (Basel, Switzerland) · 2026
    Review
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  11. Review
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  16. The evolution of the understanding of obesity over the last 100 years.International journal of obesity (2005) · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patricia Yárnoz-EsquirozDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
Laura OlazaránDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
Maite Aguas-AyesaDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
Carolina M PerdomoDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0002-5748-0581
Marta García-GoñiDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
Camilo SilvaDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
José Antonio Fernández-FormosoCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), ISCIII, Pamplona, Spain.
Javier EscaladaDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.
Fabrizio MontecuccoFirst Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.ORCID https://orcid.org/0000-0003-0823-8729
Piero PortincasaClinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.ORCID https://orcid.org/0000-0001-5359-1471
Gema FrühbeckDepartment of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.ORCID https://orcid.org/0000-0002-8305-7154

Funding

Spanish Institute of Health ISCIII and CIBEROBN PI19/00785
6 · The paper itself

Abstract

Academic medicine fosters research that moves from discovery to translation, at the same time as promoting education of the next generation of professionals. In the field of obesity, the supposed integration of knowledge, discovery and translation research to clinical care is being particularly hampered. The classification of obesity based on the body mass index does not account for several subtypes of obesity. The lack of a universally shared definition of "obesities" makes it impossible to establish the real burden of the different obesity phenotypes. The individual's genotype, adipotype, enterotype and microbiota interplays with macronutrient intake, appetite, metabolism and thermogenesis. Further investigations based on the concept of differently diagnosed "obesities" are required.

Indexed as

ObesityBody Mass IndexHumansdysfunctional adipose tissuemetabolically healthy obesitynon-communicable diseases (NCDs)Obesity phenotypesprecision medicineSarcopenic obesity

Identifiers

PMID35514242
PMCPMC9285368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.