Evidence map›Paper›PMID 35514167›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Design, synthesis, biological evaluation and QSAR analysis of novel

Anja Beč, Marija Mioč, Branimir Bertoša, Marija Kos, Patricia Debogović, Marijeta Kralj, Kristina Starčević, Marijana Hranjec

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anja BečDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.ORCID 0000-0003-0887-7950
Marija MiočDivision of Molecular Medicine, Ruđer Bošković Institute, Zagreb, Croatia.ORCID 0000-0001-5290-6945
Branimir BertošaDepartment of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.ORCID 0000-0002-4540-5648
Marija KosDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.ORCID 0000-0002-6265-315X
Patricia DebogovićDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.
Marijeta KraljDivision of Molecular Medicine, Ruđer Bošković Institute, Zagreb, Croatia.ORCID 0000-0002-7165-2722
Kristina StarčevićDepartment of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia.ORCID 0000-0002-2606-7807
Marijana HranjecDepartment of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.ORCID 0000-0002-3994-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a result of our previous research focussed on benzimidazoles, herein we present design, synthesis, QSAR analysis and biological activity of novel N-substituted benzimidazole derived carboxamides. Carboxamides were designed to study the influence of the number of methoxy groups, the type of the substituent placed at the benzimidazole core on biological activity. Pronounced antioxidative activity displayed unsubstituted

Indexed as

Antineoplastic AgentsQuantitative Structure-Activity RelationshipAntioxidantsBenzimidazolesCell ProliferationDrug Screening Assays, AntitumorStructure-Activity RelationshipAntineoplastic AgentsAntioxidantsbenzimidazoleBenzimidazolesAntioxidant activityantiproliferative activitybenzimidazolescarboxamidesQSARROS

Identifiers

PMID35514167
PMCPMC9090388

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.