Evidence map›Paper›PMID 35514116›Full record

ArticleToxicologic pathology2022

Toxicity and Local Tolerance of a Novel Spike Protein RBD Vaccine Against SARS-CoV-2, Produced Using the C1

Yuval Ramot, Noam Kronfeld, Yakir Ophir, Nati Ezov, Sheli Friedman, Markku Saloheimo, Marika Vitikainen, Hanna Ben-Artzi, Avi Avigdor, Ronen Tchelet and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Toxicologic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Yuval RamotThe Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.ORCID 0000-0002-8606-8385
Noam KronfeldEnvigo CRS Israel Limited, Ness Ziona, Israel.
Yakir OphirIsrael Institute for Biological Research, Ness Ziona, Israel.
Nati EzovEnvigo CRS Israel Limited, Ness Ziona, Israel.
Sheli FriedmanEnvigo CRS Israel Limited, Ness Ziona, Israel.
Markku SaloheimoTechnical Research Centre of Finland Ltd., Espoo, Finland.
Marika VitikainenTechnical Research Centre of Finland Ltd., Espoo, Finland.
Hanna Ben-ArtziBTG-Biotechnology General (Israel) Ltd., Kiryat Malachi, Israel.
Avi AvigdorBTG-Biotechnology General (Israel) Ltd., Kiryat Malachi, Israel.
Ronen TcheletDyadic International, Inc., Jupiter, Florida, USA.
Noelia Valbuena CrespoDyadic International, Inc., Jupiter, Florida, USA.
Mark EmalfarbDyadic International, Inc., Jupiter, Florida, USA.
Abraham NyskaTel Aviv University, Tel Aviv, Israel.
VTT Technical Research Centre of Finland · FIHebrew University of Jerusalem · ILIsrael Institute for Biological Research · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) has caused the ongoing COVID-19 pandemic and there is a growing demand for safe and effective vaccines. The thermophilic

Indexed as

COVID-19SARS-CoV-2AnimalsCOVID-19 VaccinesHumansPandemicsRabbitsSpike Glycoprotein, CoronavirusCOVID-19 VaccinesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2C1COVID-19rabbitsRBDsafetySARS-CoV-2Thermothelomyces heterothallicatoxicityvaccine

Identifiers

PMID35514116
PMCPMC9128004
OpenAlexW4229075543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.