Evidence map›Paper›PMID 35513948›Full record

ArticlePsychological medicine2023

A lifespan perspective on depression in the postpartum period in a racially and socioeconomically diverse sample of young mothers.

Alison E Hipwell, Irene Tung, Robert T Krafty, Audrey W Leong, Meredith Spada, Hope Vaccaro, Sarah C Homitsky, Eydie Moses-Kolko, Kate Keenan

Open access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Postpartum Depression in Young Mothers in Urban and Rural Indonesia.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Alison E HipwellDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-7179-1151
Irene TungDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0003-1263-066X
Robert T KraftyDepartment of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, USA.ORCID https://orcid.org/0000-0003-1478-6430
Audrey W LeongDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-5050-8927
Meredith SpadaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0001-5566-3029
Hope VaccaroDepartment of Psychological Sciences, Case Western University, Cleveland, OH, USA.
Sarah C HomitskyWomen's Behavioral Health, Allegheny Health Network, Pittsburgh, PA, USA.
Eydie Moses-KolkoDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0002-9443-2036
Kate KeenanDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-0333-6162
University of Pittsburgh · USAllegheny Health Network · USCase Western Reserve University · USEmory University · USUniversity of Chicago · US

Funding

The Development of Conduct Disorder in GirlsR01MH056630 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOEBER, ROLF · 1998 to 2012
$18.9M
Resilience to prenatal stress: Implications for offspring health and neurodevelopmentUH3OD023244 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALISON E HIPWELL · 2018 to 2026
$15.1M
Resilience to prenatal stress: Implications for offspring health and neurodevelopmentUG3OD023244 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E · 2016 to 2024
$8.3M
Preconception and prenatal stress effects on cardiovascular disease risk in black women - Diversity SupplementR01HL157787 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E, LEVINE, MICHELE D · 2020 to 2024
$3.9M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
Parsing the Heterogeneity of Neural Functioning in Postpartum DepressionR01HD067185 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E, MOSES-KOLKO, EYDIE L · 2011 to 2015
$2.5M
Maternal Stress Resilience During Pregnancy and Offspring Emotion RegulationK01MH123505 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TUNG, IRENE · 2021 to 2025
$840k
Postpartum Psychopathology and Teenage MothersK01MH071790 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E · 2005 to 2009
$731k
Impact of Maternal Caregiving on Brain-Behavior Relationships in InfantsR21MH106570 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HIPWELL, ALISON E, PHILLIPS, MARY LOUISE · 2015 to 2016
$411k
NIAAA NIH HHS T32 AA007453NICHD NIH HHS R01 HD067185NIH HHS UG3 OD023244NIH HHS UH3 OD023244NIMH NIH HHS K01 MH071790NIMH NIH HHS K01 MH123505NIMH NIH HHS R01 MH056630NIMH NIH HHS R21 MH106570
6 · The paper itself

Abstract

backgroundConsistent evidence from retrospective reports and case registry studies indicates that a history of depression is a major risk factor for depression in the peripartum period. However, longitudinal studies with racially and socioeconomically diverse samples of young mothers are lacking, and little is known about developmental patterns of depression across the lifespan that can inform preventive interventions.

methodsYoung primiparous mothers (

resultsResults revealed high levels of continuity in depression from pregnancy to postpartum, and across multiple years pre-pregnancy to postpartum. Overall, depression severity leading up to pregnancy decreased over time, but patterns of worsening or improving symptoms were not associated with depression severity in the postpartum period. Instead, area under the pre-pregnancy trajectory curve, representing cumulative lifetime depression burden, was uniquely associated with postpartum depression after adjusting for prenatal depression severity.

conclusionsDepression in the postpartum period should be considered within a lifespan perspective of risk that accumulates before conception. Clinical screening and early interventions are needed in adolescence and young adulthood to prevent the onset and persistence of depressive symptoms that could have long-term implications for peripartum health.

Indexed as

Depression, PostpartumAdolescentAdultDepressionFemaleHumansLongevityMothersPostpartum PeriodPregnancyProspective StudiesRetrospective StudiesYoung AdultCumulative effectslifespanPittsburgh Girls Studypostpartum depressionpreconception

Identifiers

PMID35513948
PMCPMC9637236
OpenAlexW4229010195

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.