ArticleBMC public health2022
Associations of physical activity with sarcopenia and sarcopenic obesity in middle-aged and older adults: the Louisiana osteoporosis study.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Persevering or quitting? A systematic review of adherence and dropout in nutrition and exercise interventions for sarcopenic obesity.Asia Pacific journal of clinical nutrition · 2026Pooled it
- Explore the optimal exercise intervention subtype for sarcopenia: a systematic review and Bayesian network meta-analysis.BMC geriatrics · 2025Pooled it
- Experiences and outcomes of older adults with obesity transitioning from gym- to home-based resistance training due to COVID-19 lockdowns: a mixed-methods analysis of a RCT.BMC geriatrics · 2025Trial
- Women's musculoskeletal health: insights from the 2024 National Academies of Sciences, Engineering, and Medicine report on chronic conditions.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Review
- Robust and Interpretable Metagenomic Modeling Through Structure-Aware Multi-View Learning and Attribution-Guided Biological Insight.Research square · 2026Article
- Device-measured and self-reported physical activity and the trajectory of cardio-renal-metabolic multimorbidity: a prospective cohort study in UK Biobank.BMC public health · 2026Article
- Barriers and facilitators to resistance and aerobic exercise among older adults with sarcopenic obesity: a qualitative study.BMC geriatrics · 2026Article
- Sarcopenic obesity in older adults: a scoping review of prevalence, assessment tools, associated factors, and interventions.Frontiers in public health · 2026Article
- Treating Sarcopenic Obesity in the Era of Incretin Therapies: Perspectives and Challenges.Diabetes · 2025Review
- Research progress on sarcopenia in the musculoskeletal system.Bone research · 2025Review
- An Attention-Aware Multi-Task Learning Framework Identifies Candidate Targets for Drug Repurposing in Sarcopenia.Journal of cachexia, sarcopenia and muscle · 2025Article
- The association between daily movement behavior and adjusted handgrip strength in post-menopausal women.Frontiers in nutrition · 2025Article
- Variability in muscle function deficits and clinical identification of sarcopenic obesity in older adults with type 2 diabetes.Frontiers in medicine · 2025Article
- Multi-View Integrative Approach For Imputing Short-Chain Fatty Acids and Identifying Key factors predicting Blood SCFA.bioRxiv : the preprint server for biology · 2024Article
- Nutritional Management and Physical Activity in the Treatment of Sarcopenic Obesity: A Review of the Literature.Nutrients · 2024Review
- Sarcopenic obesity in older adults: a clinical overview.Nature reviews. Endocrinology · 2024Review
- The Impact of the Physical Activity Level on Sarcopenic Obesity in Community-Dwelling Older Adults.Healthcare (Basel, Switzerland) · 2024Article
- Physical Activity, Sedentary Behavior, Fruit and Vegetable Consumption, and Sarcopenia in Older Chinese Adults: A Cross-Sectional Study.Nutrients · 2023Article
- Polyamines and Physical Activity in Musculoskeletal Diseases: A Potential Therapeutic Challenge.International journal of molecular sciences · 2023Review
- The mediating role of inflammaging between mitochondrial dysfunction and sarcopenia in aging: a review.American journal of clinical and experimental immunology · 2023Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundThis study examined the associations between physical activity, obesity, and sarcopenia in middle-aged and older adults.
methodsWe analyzed the data of 8, 919 study participants aged between 45 to 97 (mean age = 57.2 ± 8.8) from a Southern state in the United States. Self-reported physical activity was classified to regular exercise ≥ 3 times/week, < 3 times/week, and no regular exercise. Associations between physical activity, obesity and sarcopenia were explored with generalized linear models and ordinal logistic regressions stratified by age (middle-aged and older adults) and gender adjusting for covariates.
resultsIn middle-aged and older adults, all examined obesity related traits (e.g., body mass index, waist circumference) were inversely associated with physical activity levels (p < 0.01) in both genders. Exercising ≥ 3 times/week was negatively associated with lean mass indicators (e.g., appendicular lean mass) in middle-aged and older females (p < 0.01), while the negative associations become positive after adjusting for weight. Positive associations between physical activity and grip strength were only found in middle-aged males (p < 0.05). Ordinal logistic regression revealed that those exercising ≥ 3 times/week were less likely to have obesity, sarcopenia, and sarcopenia obesity in all groups (p < 0.01), except for sarcopenia in older males and females (p > 0.05). Positive associations of exercising < 3 times/week with sarcopenia and sarcopenia obesity were only found in middled adults.
conclusionThe associations of exercise frequency with obesity and sarcopenia vary considerably across gender and age groups. Exercise programs need to be individualized to optimize health benefits. Future research exploring physical activity strategies to balance weight reduction and lean mass maintaining is warranted in middle-aged and especially older adults.
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