SynthesisInternational urology and nephrology2022
Dialysis or kidney transplantation in older adults? A systematic review summarizing functional, psychological, and quality of life-related outcomes after start of kidney replacement therapy.
Synthesis in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Outcome after renal transplantation utilizing octogenarian donors- retrospective single-center analysis within the Eurotransplant region.Langenbeck's archives of surgery · 2026Article
- [Journal Club].Zeitschrift fur Gerontologie und Geriatrie · 2026Article
- Kidney Transplantation over 65 Years: Clinical and Immunological Long-Term Outcomes-Single Center Experience.Geriatrics (Basel, Switzerland) · 2026Article
- Outcomes Following Alemtuzumab Induction in Deceased Donor Kidney Transplantation According to Recipient Age Categories: A Single Center Report.Clinical transplantation · 2026Article
- Association of 90-day post-transplant low magnesium exposure with new-onset post-transplant diabetes mellitus in older kidney transplant recipients.BMC geriatrics · 2026Article
- Expanding perspectives on preemptive high-KDPI kidney transplantation in older adults.International urology and nephrology · 2026Article
- Evaluating outcomes of preemptive kidney transplant in patients over 65 using high-KDPI kidneys compared to non-preemptive recipients.International urology and nephrology · 2026Article
- Clinical management of cancer after kidney transplantation.Frontiers in immunology · 2026Review
- Supporting Shared Decision-Making in Life-Altering Kidney Therapy Decisions for Older Adults: A Review.JAMA internal medicine · 2025Review
- Article
- The Interplay Between Parental Bonding and Health-Related Quality of Life in Kidney Transplant Recipients: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- The evaluation of kidney transplant candidates prior to waitlisting: a scoping review.Clinical kidney journal · 2025Article
- SupervisedWorld journal of transplantation · 2024Article
- Interstitial Foci Expression of Indoleamine 2,3-Dioxygenase 1: A Potential Biomarker for Kidney Transplant Rejection.Journal of clinical medicine · 2024Article
- Heterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling.Scientific reports · 2024Article
- Choosing conservative care in advanced chronic kidney disease: a scoping review of patients' perspectives.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Clinical response to nonsurgical periodontal therapy is associated with decreased serum leukocyte count and uric acid levels in kidney transplant recipients.Journal of applied oral science : revista FOB · 2024Article
- Indoleamine 2,3-Dioxygenase 1 (IDO1) in Kidney Transplantation: A Guardian against Rejection.Journal of clinical medicine · 2023Article
- The effects of a physical exercise program in Chinese kidney transplant recipients: a prospective randomised controlled trial.Clinical kidney journal · 2023Article
- Kidney Transplant Outcomes in Elderly Population: A Systematic Review and Meta-analysis.European urology open science · 2023Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn older patients, the choice between kidney transplantation (KT) and dialysis may be complicated because of a high prevalence of comorbidities and geriatric syndromes. Ideally, this decision-making process focusses on older patients' outcome priorities, which frequently include functional, psychological, and quality of life (QOL)-related outcomes. PURPOSE: This systematic review aims to summarize functional, psychological (including cognition), and QOL-related outcomes after start of kidney replacement therapy (KRT) in older adults.
methodsWe searched PubMed and Embase for research that investigated change in these variables after start of KRT in patients aged ≥ 60 years. Data were extracted using the summary measures reported in the individual studies. Risk of bias was assessed with the ROBINS-I tool.
resultsSixteen observational studies (prospective n = 9, retrospective n = 7; KT-recipients n = 3, dialysis patients n = 13) were included. The results show that QOL improves in the majority of the older KT recipients. After start of dialysis, QOL improved or remained stable for most patients, but this seems less prevalent than after KT. Functional status decreases in a substantial part of the older dialysis patients. Furthermore, the incidence of serious fall injuries increases after start of dialysis. Nutritional status seems to improve after start of dialysis.
conclusionThe interpretability and comparability of the included studies are limited by the heterogeneity in study designs and significant risk of bias in most studies. Despite this, our overview of functional, psychological (including cognition), and QOL-related outcomes is useful for older adults and their clinicians facing the decision between KT and dialysis.
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