ArticleIntensive care medicine2022
In search of the Holy Grail: identifying the best PEEP in ventilated patients.
Article in Intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05583461 (Ventilator-induced Right Ventricular Injury During Electrical Impedance Tomography-based Positive End-expiratory Pressure Titration in Patients With Acute Respiratory Distress Syndrome), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ventilator-induced Right Ventricular Injury During Electrical Impedance Tomography-based Positive End-expiratory Pressure Titration in Patients With Acute Respiratory Distress Syndrome: a Pilot Physiological Study.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Electrical impedance tomography for PEEP titration in ARDS patients: a systematic review and meta-analysis.Journal of clinical monitoring and computing · 2025Pooled it
- The "mechanical paradox" unveiled: a physiological study.Critical care (London, England) · 2025Trial
- Extracellular Vesicles from Bronchoalveolar Lavage Fluid Indicate Early Biomarker Potential and Differentiate Local Lung Injury in a Porcine Model of Asymmetric Acute Lung Injury.International journal of molecular sciences · 2026Article
- Individualized PEEP titration guided by static lung compliance reduces postoperative atelectasis in elderly patients during laparoscopic Trendelenburg surgery: a randomized controlled trial.Perioperative medicine (London, England) · 2026Article
- The role of mechanical power in lung ventilation for the prevention of ventilator-induced lung injury: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Setting PEEP in patients with COVID-19-related ARDS: a physiological comparison between methods.Intensive care medicine experimental · 2026Article
- Optimizing Positive End-Expiratory Pressure in Asymmetric Acute Lung Injury in a Porcine Model: The Role of Transpulmonary Pressure.International journal of molecular sciences · 2025Article
- Acute Respiratory Distress Syndrome: Pathophysiological Insights, Subphenotypes, and Clinical Implications-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Individualized PEEP can improve both pulmonary hemodynamics and lung function in acute lung injury.Critical care (London, England) · 2025Article
- The potential risk of ventilator-induced lung injury from five different PEEP titration techniques in ARDS.Frontiers in medicine · 2025Article
- Stepwise positive end-expiratory pressure titration modulates respiratory mechanics and mechanical power in mechanically ventilated adults.Critical care science · 2025Article
- Impact of circuit configuration on the mechanical performance of CPAP therapy devices: an experimental study.Frontiers in medical technology · 2025Article
- Positive end-expiratory pressure management in patients with severe ARDS: implications of prone positioning and extracorporeal membrane oxygenation.Critical care (London, England) · 2024Review
- Positive end-expiratory pressure optimization in ARDS: physiological evidence, bedside methods and clinical applications.Intensive care medicine · 2024Article
- Effects of positive end-expiratory pressure on intracranial pressure, cerebral perfusion pressure, and brain oxygenation in acute brain injury: Friend or foe? A scoping review.Journal of intensive medicine · 2024Article
- Quantifying heterogeneity in an animal model of acute respiratory distress syndrome, a comparison of inspired sinewave technique to computed tomography.Scientific reports · 2024Article
- Physical and respiratory therapy in the critically ill patient with obesity: a narrative review.Frontiers in medicine · 2024Review
- Article
- Newly Proposed Diagnostic Criteria for Acute Respiratory Distress Syndrome: Does Inclusion of High Flow Nasal Cannula Solve the Problem?Journal of clinical medicine · 2023Article
- Practical Aspects of Esophageal Pressure Monitoring in Patients with Acute Respiratory Distress Syndrome.Journal of personalized medicine · 2023Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.