Evidence map›Paper›PMID 35513589›Full record

ArticleAnnals of surgical oncology2022

Surgery Refusal Among Black and Hispanic Women with Non-Metastatic Breast Cancer.

Theresa Relation, Amara Ndumele, Oindrila Bhattacharyya, James L Fisher, Yaming Li, Samilia Obeng-Gyasi, Mariam F Eskander, Allan Tsung, Bridget A Oppong

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Theresa RelationDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0002-3176-3663
Amara NdumeleCollege of Medicine, The Ohio State University, Columbus, OH, USA.
Oindrila BhattacharyyaDepartment of Economics, Indiana University Purdue University, Indianapolis, IN, USA.
James L FisherJames Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, OH, USA.
Yaming LiDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Samilia Obeng-GyasiDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Mariam F EskanderDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Allan TsungDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA.
Bridget A OppongDivision of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, OH, USA. bridget.oppong@osumc.edu.
The Ohio State University · USRegenstrief Institute · USThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have shown a lower receipt of treatment among minority women with non-metastatic breast cancer. Those who refuse surgery have increased disease-specific mortality, contributing to disproportionately higher breast cancer mortality in non-Hispanic black (NHB) and Hispanic women. This study aimed to assess surgery refusal in these groups, identify factors associated with surgery refusal, and characterize the association between surgery refusal and survival.

methodsSurveillance, Epidemiology, and End Results (SEER) Program data from 2005 to 2015 for NHB and Hispanic women with a diagnosis of non-metastatic breast cancer (n = 113,987) was divided into data of those who underwent surgery and data of those who refused surgery. Sociodemographic and tumor clinical/pathologic differences were analyzed by multivariate logistic regression of predictors of surgery refusal and Cox-proportional hazard model of disease-specific mortality.

resultsOf 799 patients who refused surgery, 562 were NHB and 237 were Hispanic. The percentage of patients refusing surgery increased from 0.6% in 2005 to 0.9% in 2015. The women who refused surgery were more likely to be older than 81 years, less likely to be married, and more likely to be uninsured or have Medicaid. The refusers presented with more advanced disease and more frequent estrogen receptor-positivity (ER+) and progesterone receptor-positivity (PR+) subtype on histology. Breast cancer-specific mortality increased significantly with surgery omission. Surgery refusal was independently associated with NHB race.

conclusionSurgery refusal among NHB and Hispanic women with potentially curable non-metastatic breast cancer is rising, especially among NHB women, women older than 60 years, single women, and women with a later stage of disease at diagnosis. Additional studies are needed to analyze qualitative data in these populations and their underlying health beliefs, communication needs, and possible use of alternative medicine.

Indexed as

Breast NeoplasmsBlack or African AmericanFemaleHispanic or LatinoHumansReceptors, EstrogenReceptors, ProgesteroneUnited StatesReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID35513589
OpenAlexW4229030288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.