ArticleNature communications2022
ON/OFF domains shape receptive field structure in mouse visual cortex.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Conformal and adhesive gel for stable electrophysiology on hairy animals without shaving.Nature communications · 2026Article
- Optogenetic stimulation of pyramidal neurons in the rat primary visual cortex modulates ON- and OFF- receptive field areas independently.Scientific reports · 2025Article
- A column-like organization for ocular dominance in mouse visual cortex.Nature communications · 2025Article
- Cortical direction selectivity increases from the input to the output layers of visual cortex.PLoS biology · 2025Article
- Identification of movie encoding neurons enables movie recognition AI.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Contrast gain control is a reparameterization of a population response curve.Journal of neurophysiology · 2024Article
- Contrast gain control is a reparameterization of a population response curve.bioRxiv : the preprint server for biology · 2024Article
- Visual neurons recognize complex image transformations.bioRxiv : the preprint server for biology · 2024Article
- Binocular receptive-field construction in the primary visual cortex.Current biology : CB · 2024Article
- Self-organization of modular activity in immature cortical networks.Nature communications · 2024Article
- Stimulus-dependent differences in cortical versus subcortical contributions to visual detection in mice.Current biology : CB · 2024Article
- Dynamic Recruitment of the Feedforward and Recurrent Mechanism for Black-White Asymmetry in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- High-resolution structural and functional retinal imaging in the awake behaving mouse.Communications biology · 2023Article
- Thalamocortical boutons cluster by ON/OFF responses in mouse primary visual cortex.Journal of neurophysiology · 2023Article
- The brain-inspired decoder for natural visual image reconstruction.Frontiers in neuroscience · 2023Article
- ON and OFF Signaling Pathways in the Retina and the Visual System.Frontiers in ophthalmology · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In higher mammals, thalamic afferents to primary visual cortex (area V1) segregate according to their responses to increases (ON) or decreases (OFF) in luminance. This organization induces columnar, ON/OFF domains postulated to provide a scaffold for the emergence of orientation tuning. To further test this idea, we asked whether ON/OFF domains exist in mouse V1. Here we show that mouse V1 is indeed parceled into ON/OFF domains. Interestingly, fluctuations in the relative density of ON/OFF neurons on the cortical surface mirror fluctuations in the relative density of ON/OFF receptive field centers on the visual field. Moreover, the local diversity of cortical receptive fields is explained by a model in which neurons linearly combine a small number of ON and OFF signals available in their cortical neighborhoods. These findings suggest that ON/OFF domains originate in fluctuations of the balance between ON/OFF responses across the visual field which, in turn, shapes the structure of cortical receptive fields.
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