Evidence map›Paper›PMID 35512834›Full record

ArticleLife science alliance2022

Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in

Peter J Stogios, Sean D Liston, Cameron Semper, Bradley Quade, Karolina Michalska, Elena Evdokimova, Shane Ram, Zbyszek Otwinowski, Dominika Borek, Leah E Cowen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Peter J StogiosDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada.
Sean D ListonDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.ORCID 0000-0002-6218-2247
Cameron SemperDepartment of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.ORCID 0000-0003-2025-799X
Bradley QuadeDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Karolina MichalskaStructural Biology Center, X-ray Science Division, Argonne National Laboratory, Argonne, IL, USA.ORCID 0000-0001-7140-3649
Elena EvdokimovaDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada.
Shane RamDepartment of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Canada.
Zbyszek OtwinowskiDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Dominika BorekDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-4321-6253
Leah E CowenDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.ORCID 0000-0001-5797-0110
Alexei SavchenkoDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada alexei.savchenko@ucalgary.ca.ORCID 0000-0002-5256-9237
University of Toronto · CAThe University of Texas Southwestern Medical Center · USUniversity of Calgary · CAArgonne National Laboratory · US

Funding

From complex data to complex structures: new methods for structural biologyR35GM145365 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ZBYSZEK OTWINOWSKI · 2022 to 2026
$2.3M
NIAID NIH HHS HHSN272201700060CNIGMS NIH HHS R35 GM145365
6 · The paper itself

Abstract

In the human fungal pathogen

Indexed as

Candida albicansHumans

Identifiers

PMID35512834
PMCPMC9074039
OpenAlexW4229021135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.