Evidence map›Paper›PMID 35512347›Full record

ArticleBritish medical bulletin2022

Efficacy and safety of drugs used for 'assisted dying'.

Ana Worthington, Ilora Finlay, Claud Regnard

Open access · hybridAbstract read
In one paragraph

Article in British medical bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Physician-Assisted Dying Witnessed by Emergency Medical Services: A Case Report.Clinical practice and cases in emergency medicine · 2025
    Article
  7. Article
  8. Assisted dying - we can't be neutral.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  9. Canada's Medical Assistance in Dying System can Enable Healthcare Serial Killing.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2025
    Article
  10. Crossing the Rubicon: assisted dying in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ana WorthingtonUniversity of Oxford, Radcliffe Observatory Quarter, Woodstock Rd, Oxford OX1 3PG, UK.
Ilora FinlayCardiff University, Main Park Place, Cardiff CF14 2TL, UK.
Claud RegnardSt. Oswald's Hospice, Regent Avenue, Gosforth, Newcastle-upon-Tyne ME3 1EE, UK.
Cardiff University · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background'Assisted dying' is practiced in some European countries and US states. Legislation suggests that there exists an easily prescribed drug which consistently brings about death quickly and painlessly. Evidence from jurisdictions where 'assisted dying' is practiced, however, reveals that hastening patient death is not so simple. SOURCES OF DATA: This report is a collation of assisted suicide and euthanasia drug protocols published by the Canadian Association of MAiD Assessors and Providers and the Royal Dutch Medical Association, annual data reports from the USA and Canada and relevant academic publications pertaining to methods of 'assisted dying' in the USA, Belgium, Canada and Switzerland. AREAS OF AGREEMENT: A wide variety of lethal drug combinations are used for people who want their life ended, and the prevalence of complications and failures in intentionally ending life suggest that 'assisted dying' applicants are at risk of distressing deaths. AREAS OF CONTROVERSY: The efficacy and safety of 'assisted dying' drugs are currently difficult to assess, as clinician reporting is often very low. GROWING POINTS: The findings from this report reveal that little attention has been given to the problem of unmonitored prescribing and administering of lethal drug combinations, whose mode of action is unclear. AREAS TIMELY FOR DEVELOPING RESEARCH: In order to properly assess the efficacy and safety of 'assisted dying', a more thorough means of data collection regarding the drugs used must be implemented and research is urgently needed into their mode of action.

Indexed as

EuthanasiaSuicide, AssistedCanadaEuropeHumansassisted suicidedrug safetyeuthanasiainformed consent

Identifiers

PMID35512347
PMCPMC9270985
OpenAlexW4226190843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.