ArticlePlant physiology2022
The NAC transcription factor ANAC017 regulates aluminum tolerance by regulating the cell wall-modifying genes.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 57 citations in OpenAlex.
- A bHLH121/URI-ANAC017-MAT1/SAM1 regulatory cascade controls iron homeostasis in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Multi-locus genome-wide association studies of aluminum stress indices in shoot and root traits at seedling stage in Ethiopian durum wheat (Triticum turgidum ssp. durum) genotypes.BMC plant biology · 2026Article
- Overexpression ofPlants (Basel, Switzerland) · 2026Article
- Comprehensive analysis of the NAC transcription factor gene family in Sophora tonkinensis Gagnep.BMC plant biology · 2025Article
- Genome-Wide Identification of thePlants (Basel, Switzerland) · 2025Article
- Review
- GsMYB10 encoding a MYB-CC transcription factor enhances the tolerance to acidic aluminum stress in soybean.BMC plant biology · 2024Article
- Perception and processing of stress signals by plant mitochondria.The Plant journal : for cell and molecular biology · 2024Review
- Towards sustainable use of acidic soils: Deciphering aluminum-resistant mechanisms in plants.Fundamental research · 2024Review
- Combined BSA-Seq and RNA-Seq Analysis to Identify Candidate Genes Associated with Aluminum Toxicity in Rapeseed (International journal of molecular sciences · 2024Article
- Systematic Investigation of Aluminum Stress-Related Genes and Their Critical Roles in Plants.International journal of molecular sciences · 2024Review
- Transcriptional Control of Seed Life: New Insights into the Role of the NAC Family.International journal of molecular sciences · 2024Review
- Article
- Physiological and Transcriptomic Analyses Reveal Commonalities and Specificities in Wheat in Response to Aluminum and Manganese.Current issues in molecular biology · 2024Article
- Dissection of quantitative trait nucleotides and candidate genes associated with agronomic and yield-related traits under drought stress in rapeseed varieties: integration of genome-wide association study and transcriptomic analysis.Frontiers in plant science · 2024Article
- The upstream regulation of the root cell wall whenPlant signaling & behavior · 2023Article
- Overexpression of an ART1-Interacting GeneInternational journal of molecular sciences · 2023Article
- The transcription factor MYB156 controls the polar stiffening of guard cell walls in poplar.The Plant cell · 2023Article
- Transcriptome-Wide Identification and Response Pattern Analysis of theInternational journal of molecular sciences · 2023Article
- Isolation, characterization, and functional verification of salt stress response genes of NAC transcription factors inFrontiers in plant science · 2023Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aluminum (Al) toxicity is one of the key factors limiting crop production in acid soils; however, little is known about its transcriptional regulation in plants. In this study, we characterized the role of a NAM, ATAF1/2, and cup-shaped cotyledon 2 (NAC) transcription factors (TFs), ANAC017, in the regulation of Al tolerance in Arabidopsis (Arabidopsis thaliana). ANAC017 was localized in the nucleus and exhibited constitutive expression in the root, stem, leaf, flower, and silique, although its expression and protein accumulation were repressed by Al stress. Loss of function of ANAC017 enhanced Al tolerance when compared with wild-type Col-0 and was accompanied by lower root and root cell wall Al content. Furthermore, both hemicellulose and xyloglucan content decreased in the anac017 mutants, indicating the possible interaction between ANAC017 and xyloglucan endotransglucosylase/hydrolase (XTH). Interestingly, the expression of XTH31, which is responsible for xyloglucan modification, was downregulated in the anac017 mutants regardless of Al supply, supporting the possible interaction between ANAC017 and XTH31. Yeast one-hybrid, dual-luciferase reporter assay, and chromatin immunoprecipitation-quantitative PCR analysis revealed that ANAC017 positively regulated the expression of XTH31 through directly binding to the XTH31 promoter region, and overexpression of XTH31 in the anac017 mutant background rescued its Al-tolerance phenotype. In conclusion, we identified that the tTF ANAC017 acts upstream of XTH31 to regulate Al tolerance in Arabidopsis.
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