Evidence map›Paper›PMID 35512085›Full record

SynthesisBritish medical bulletin2022

Ligament Advanced Reinforcement System (LARS) synthetic graft for PCL reconstruction: systematic review and meta-analysis.

Filippo Migliorini, Andrea Pintore, Gianluca Vecchio, Francesco Oliva, Frank Hildebrand, Nicola Maffulli

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in British medical bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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  7. [Progress in prevention and treatment of knee laxity after posterior cruciate ligament reconstruction].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Filippo MiglioriniDepartment of Orthopaedics, University Clinic Aachen, RWTH Aachen University Clinic, 52064 Aachen, Germany.
Andrea PintoreDepartment of Orthopaedics, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Gianluca VecchioDepartment of Orthopaedics, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Francesco OlivaDepartment of Orthopaedics, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
Frank HildebrandDepartment of Orthopaedics, University Clinic Aachen, RWTH Aachen University Clinic, 52064 Aachen, Germany.
Nicola MaffulliDepartment of Orthopaedics, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy.
University of Salerno · ITIstituto Nazionale di Fisica Nucleare, Sezione di Bari · ITMile End Hospital · GBRWTH Aachen University · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeveral strategies are available for posterior cruciate ligament (PCL) reconstruction. SOURCE OF DATA: Recently published literature in PubMed, Google Scholar and Embase databases. AREAS OF AGREEMENT: The Ligament Advanced Reinforcement System (LARS) is a scaffold type artificial ligament, which has been widely used for ligament reconstruction of the knee. AREAS OF CONTROVERSY: Current evidence on the reliability and feasibility of LARS for primary isolated PCL reconstruction is limited. GROWING POINTS: The primary outcome of interest of the present work was to investigate the outcomes of PCL reconstruction using the LARS. The secondary outcome of interest was to compare the LARS versus four-strand hamstring tendon (4SHT) autograft for PCL reconstruction. AREAS TIMELY FOR DEVELOPING RESEARCH: LARS for primary isolated PCL reconstruction seems to be effective and safe, with results comparable to the 4SHT autograft.

Indexed as

Anterior Cruciate Ligament InjuriesPosterior Cruciate Ligament ReconstructionHumansKnee JointLigamentsReproducibility of ResultsTransplantation, AutologousTreatment OutcomegraftkneeLARSPCL reconstruction

Identifiers

PMID35512085
PMCPMC9494250
OpenAlexW4226435858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.