ArticleScience (New York, N.Y.)2022
The geometry of domain-general performance monitoring in the human medial frontal cortex.
Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Electroencephalogram activity related to psychopathological and neuropsychological symptoms in institutionalised minors: a systematic review.Acta neuropsychiatrica · 2025Pooled it
- Success versus failure in cognitive control: Meta-analytic evidence from neuroimaging studies on error processing.Neuroscience and biobehavioral reviews · 2024Pooled it
- Towards an integrative neuroscience of metacognition.Nature reviews. Neuroscience · 2026Review
- Insights into the neural mechanisms supporting cognitive stability and flexibility from human intracranial electroencephalography.Neuroscience and biobehavioral reviews · 2026Review
- Reusable modular architecture enables flexible cognitive operations in the mouse brain and artificial recurrent networks.Nature neuroscience · 2026Article
- Hierarchical and context-dependent encoding of actions in human posterior parietal and motor cortex.Cell · 2026Article
- Neural dynamics underlying minute-timescale persistent behaviour in the human brain.Nature human behaviour · 2026Article
- Low-dimensional factorized neural computations underlie risk-adaptive choices.Research square · 2026Article
- A communication subspace relays context-dependent actions from human prefrontal to motor cortex.Nature neuroscience · 2026Article
- Computational neural dynamics of goal-directed visual attention in macaques.Science advances · 2026Article
- Single-Neuron Recordings Research in Children: Ethical Considerations, Feasibility, Technical Aspects, and Scientific Opportunities.Pediatric neurosurgery · 2026Review
- Cognitive training shapes brain plasticity and schematic representations.Behavioral and brain functions : BBF · 2025Review
- Hierarchical and Context-Dependent Encoding of Actions in Human Posterior Parietal and Motor Cortex.bioRxiv : the preprint server for biology · 2025Article
- Reusable modular architecture enables flexible cognitive operations.Research square · 2025Article
- Altered Reward Processing in Obsessive-Compulsive Disorder: Insights From Active and Observational Learning.Psychophysiology · 2025Article
- Computational and Neuronal Basis of Visual Confidence.Annual review of vision science · 2025Review
- Cognitive processes are disentangled at cortex-wide scales.bioRxiv : the preprint server for biology · 2025Article
- Gamma synchronization between the medial temporal lobe and medial frontal cortex for goal-directed visual attention in humans.Cell reports · 2025Article
- Meta-Reinforcement Learning reconciles surprise, value, and control in the anterior cingulate cortex.PLoS computational biology · 2025Article
- Distractor-specific control adaptation in multidimensional environments.Nature human behaviour · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Controlling behavior to flexibly achieve desired goals depends on the ability to monitor one's own performance. It is unknown how performance monitoring can be both flexible, to support different tasks, and specialized, to perform each task well. We recorded single neurons in the human medial frontal cortex while subjects performed two tasks that involve three types of cognitive conflict. Neurons encoding conflict probability, conflict, and error in one or both tasks were intermixed, forming a representational geometry that simultaneously allowed task specialization and generalization. Neurons encoding conflict retrospectively served to update internal estimates of conflict probability. Population representations of conflict were compositional. These findings reveal how representations of evaluative signals can be both abstract and task-specific and suggest a neuronal mechanism for estimating control demand.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.