Evidence map›Paper›PMID 35511729›Full record

Observational studyAge and ageing2022

COVID-19 risk factors amongst 14,786 care home residents: an observational longitudinal analysis including daily community positive test rates of COVID-19, hospital stays and vaccination status in Wales (UK) between 1 September 2020 and 1 May 2021.

Joe Hollinghurst, Robyn Hollinghurst, Laura North, Amy Mizen, Ashley Akbari, Sara Long, Ronan A Lyons, Rich Fry

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joe HollinghurstSwansea University, Wales, UK.ORCID 0000-0002-3556-2017
Robyn HollinghurstSwansea University, Wales, UK.
Laura NorthSwansea University, Wales, UK.
Amy MizenSwansea University, Wales, UK.
Ashley AkbariSwansea University, Wales, UK.
Sara LongSwansea University, Wales, UK.
Ronan A LyonsPopulation Data Science, Swansea University, Wales, UK.
Rich FrySwansea University, Wales, UK.ORCID 0000-0002-7968-6679
Swansea University · GB

Funding

British Heart FoundationHCRW_ SCF-18-1504Medical Research Council MC_PC_20058Medical Research Council MR/V028367/1Wellcome Trust
6 · The paper itself

Abstract

backgroundCOVID-19 vaccinations have been prioritised for high risk individuals.

aimDetermine individual-level risk factors for care home residents testing positive for SARS-CoV-2. STUDY

designLongitudinal observational cohort study using individual-level linked data from the Secure Anonymised Information Linkage (SAIL) databank.

settingFourteen thousand seven hundred and eighty-six older care home residents (aged 65+) living in Wales between 1 September 2020 and 1 May 2021. Our dataset consisted of 2,613,341 individual-level daily observations within 697 care homes.

methodsWe estimated odds ratios (ORs [95% confidence interval]) using multilevel logistic regression models. Our outcome of interest was a positive SARS-CoV-2 PCR test. We included time-dependent covariates for the estimated community positive test rate of COVID-19, hospital inpatient status, vaccination status and frailty. Additional covariates were included for age, sex and specialist care home services.

resultsThe multivariable regression model indicated an increase in age (OR 1.01 [1.00,1.01] per year), community positive test rate (OR 1.13 [1.12,1.13] per percent increase), hospital inpatients (OR 7.40 [6.54,8.36]), and residents in care homes with non-specialist dementia care (OR 1.42 [1.01,1.99]) had an increased odds of a positive test. Having a positive test prior to the observation period (OR 0.58 [0.49,0.68]) and either one or two doses of a vaccine (0.21 [0.17,0.25] and 0.05 [0.02,0.09], respectively) were associated with a decreased odds.

conclusionsCare providers need to remain vigilant despite the vaccination rollout, and extra precautions should be taken when caring for the most vulnerable. Minimising potential COVID-19 infection for care home residents when admitted to hospital should be prioritised.

Indexed as

COVID-19HumansLength of StayRisk FactorsSARS-CoV-2VaccinationWalescare homesCOVID-19hospital infectionolder peoplePCR testsvaccination

Identifiers

PMID35511729
PMCPMC9070807
OpenAlexW4226180304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.