Evidence map›Paper›PMID 35511673›Full record

ArticleHaematologica2022

β adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.

Remya Nair, Vimal Subramaniam, Benjamin G Barwick, Vikas A Gupta, Shannon M Matulis, Sagar Lonial, Lawrence H Boise, Ajay K Nooka, Kuzhali Muthumalaiappan, Mala Shanmugam

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Remya NairDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Vimal SubramaniamDepartment of Surgery, Loyola University Medical Center, Maywood, Illinois, USA; Burn and Shock Trauma Research Institute, Loyola University Chicago, Chicago, Illinois.
Benjamin G BarwickDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Vikas A GuptaDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Shannon M MatulisDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Sagar LonialDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Lawrence H BoiseDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Ajay K NookaDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA.
Kuzhali MuthumalaiappanDepartment of Surgery, Loyola University Medical Center, Maywood, Illinois, USA; Burn and Shock Trauma Research Institute, Loyola University Chicago, Chicago, Illinois.
Mala ShanmugamDepartment of Hematology and Medical Oncology, Winship Cancer Institute, School of Medicine, Emory University, Atlanta, GA. mala.shan@emory.edu.
Emory University · USLoyola University Chicago · USLoyola University Medical Center · US

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Ragini Reiney Kudchadkar · 2009 to 2026
$47.5M
Implications of Metabolic Regulation of BCL-2 Dependence for Myeloma TherapyR01CA208328 · NCI · EMORY UNIVERSITY · PI SHANMUGAM, MALATHY (MALA) · 2017 to 2021
$1.9M
Mechanisms of Impaired Erythropoiesis in Post Burn Anemia of Critical IllnessR56DK097760 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI MUTHUMALAIAPPAN, KUZHALI · 2018 to 2018
$100k
NCI NIH HHS P30 CA138292NCI NIH HHS R01 CA208328NIDDK NIH HHS R56 DK097760
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple MyelomaAdrenergic AgentsHematopoietic Stem CellsHumansAdrenergic Agents

Identifiers

PMID35511673
PMCPMC9425311
OpenAlexW4229058376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.