Evidence map›Paper›PMID 35511403›Full record

ArticleCJEM2022

The impact of post-intubation hypotension on length of stay and mortality in adult and geriatric patients: a cohort study.

Marcel Émond, David Lachance-Perreault, Valérie Boucher, Pierre-Hugues Carmichael, Jeanne Turgeon, Audrey-Anne Brousseau, Alexandra Akoum, Jean-Nicolas Tourigny, Natalie Le Sage

Abstract read
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In one paragraph

Article in CJEM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Marcel ÉmondCHU de Québec-Université Laval Research Centre, 18e rue, 1401, H-608, Quebec, QC, G1J 1Z4, Canada. marcelemond1@me.com.ORCID 0000-0001-7158-8110
David Lachance-PerreaultDépartement de médecine familiale et de médecine d'urgence, Faculté de médecine, Université Laval, Quebec, QC, Canada.
Valérie BoucherCHU de Québec-Université Laval Research Centre, 18e rue, 1401, H-608, Quebec, QC, G1J 1Z4, Canada.
Pierre-Hugues CarmichaelCentre d'excellence sur le vieillissement de Québec, Centre intégré universitaire de santé et services sociaux (CIUSSS) de la Capitale-Nationale, Quebec, QC, Canada.
Jeanne TurgeonDépartement de médecine familiale et de médecine d'urgence, Faculté de médecine, Université Laval, Quebec, QC, Canada.
Audrey-Anne BrousseauDépartement de médecine familiale et médecine d'urgence, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada.
Alexandra AkoumDépartement de médecine familiale et de médecine d'urgence, Faculté de médecine, Université Laval, Quebec, QC, Canada.
Jean-Nicolas TourignyCHU de Québec-Université Laval Research Centre, 18e rue, 1401, H-608, Quebec, QC, G1J 1Z4, Canada.
Natalie Le SageCHU de Québec-Université Laval Research Centre, 18e rue, 1401, H-608, Quebec, QC, G1J 1Z4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association between standard post-intubation hypotension (< 90 mmHg) and in-hospital mortality. Secondary objectives were to evaluate the association of post-intubation hypotension and length of stay and to assess the impact of increasing post-intubation hypotension threshold to 110 mmHg on hospital length of stay and 48 h-mortality in patients aged ≥ 65 years.

methodsDesign and setting: A cohort of patients admitted in a level-1 trauma centre emergency department (ED) between November 2011 and July 2016. INCLUSION CRITERIA: aged ≥ 16 with available pre-intubation vital signs, intubation performed in ≤ 3 attempts with no surgical access needed. MEASURES: Prospective electronic data collection was used for clinical data. MAIN OUTCOME: 48-h in-hospital mortality. SECONDARY OUTCOME: hospital length of stay. ANALYSES: Univariate and multivariate analyses.

resultsA total of 586 patients were included. The mean age was 56.3 ± 18.8 years and 37% were aged ≥ 65 years. Within 60 min of intubation, 224 (38%) patients had at least one systolic blood pressure measure < 90 mmHg and 164(28%) had at least two measures. The < 110 mmHg threshold showed a total of 377 patients (64%) had at least one systolic blood pressure measure < 110 mmHg and 286 (49%) had at least two measures. We found no significant difference in the risk of mortality overall and in stratified-age groups and no association with increased hospital length of stay using both post-intubation hypotension thresholds.

conclusionPost-intubation hypotension was recorded in one out of three patients in the ED but we found no association between post-intubation hypotension and 48-h in-hospital mortality overall in adults or geriatric patients.

Indexed as

HypotensionIntubation, IntratrachealAdultAgedCohort StudiesEmergency Service, HospitalHospital MortalityHumansLength of StayMiddle AgedProspective StudiesEmergency medicineHypotensionIntubation

Identifiers

PMID35511403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.