Evidence map›Paper›PMID 35511384›Full record

ArticleJournal of fluorescence2022

Establishment and Clinical Application of a Highly Sensitive Time-Resolved Fluorescence Immunoassay for Tumor-Associated Trypsinogen-2.

Xindong Chen, Jianfeng Hong, Han Zhao, Zhongyi Xiang, Yuan Qin, Xiumei Zhou, Yigang Wang, Liping Zheng, Pengguo Xia, Hongming Fang and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Xindong Chen *College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Jianfeng Hong *Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Han Zhao *The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Nanjing, China.
Zhongyi XiangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Yuan QinCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Xiumei ZhouCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Yigang WangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Liping ZhengAffiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
Pengguo XiaCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.
Hongming FangAffiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China. 3295988078@qq.com.
Yingwei ZhuThe Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University, Nanjing, China. zhuyingw2020@163.com.
Biao HuangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China. jswxhb@163.com.ORCID http://orcid.org/0000-0003-1883-0670
Zhejiang Sci-Tech University · CNAffiliated Hospital of Hangzhou Normal University · CNWuxi No.2 People's Hospital · CNZhejiang Chinese Medical University · CN

Funding

the Key Research and Development Program of Zhejiang Province No. 2020C03066the Opening Project of Zhejiang Provincial Preponderant and Characteristic Subject of Key University (Traditional Chinese Pharmacology), Zhejiang Chinese Medical University No. ZYAOXYB20190040the Social Development Fund of Zhejiang Province No. LGF20H200008"Two Hundreds" Young and Middle-aged Medical Key Talent Project of Wuxi No. BJ2020027
6 · The paper itself

Abstract

To establish a rapid and highly sensitive assay for tumor-associated trypsinogen-2 (TAT-2) based on the time-resolved fluorescence immunoassay (TRFIA) and evaluate its potential clinical value in patients with lung cancer. The double-antibody sandwich method was used in detecting TAT-2 antigen concentrations, and two types of TAT-2 antibodies (coating antibodies and Eu

Indexed as

Lung NeoplasmsTrypsinogenFluoroimmunoassayHumansSensitivity and SpecificityTrypsinTrypsinTrypsinogenDouble-antibody sandwich methodLung cancerTime-resolved fluorescence immunoassayTumor-associated trypsinogen-2

Identifiers

PMID35511384
OpenAlexW4229017186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.