Evidence map›Paper›PMID 35511284›Full record

ArticleEuropean journal of nutrition2022

Dietary score associations with markers of chronic low-grade inflammation: a cross-sectional comparative analysis of a middle- to older-aged population.

Seán R Millar, Pilar Navarro, Janas M Harrington, Nitin Shivappa, James R Hébert, Ivan J Perry, Catherine M Phillips

Open access · hybridAbstract read
In one paragraph

Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Seán R MillarHRB Centre for Health and Diet Research, School of Public Health, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0003-4453-8446
Pilar NavarroSchool of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin 4, Ireland.ORCID http://orcid.org/0000-0002-6293-2570
Janas M HarringtonHRB Centre for Health and Diet Research, School of Public Health, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0002-6238-7031
Nitin ShivappaCancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina and Connecting Health Innovations LLC, Columbia, SC, USA.ORCID http://orcid.org/0000-0003-0441-8896
James R HébertCancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina and Connecting Health Innovations LLC, Columbia, SC, USA.ORCID http://orcid.org/0000-0002-0677-2672
Ivan J PerryHRB Centre for Health and Diet Research, School of Public Health, University College Cork, Cork, Ireland.ORCID http://orcid.org/0000-0002-4965-9792
Catherine M PhillipsHRB Centre for Health and Diet Research, School of Public Health, University College Cork, Cork, Ireland. catherine.phillips@ucd.ie.ORCID http://orcid.org/0000-0003-4916-4463
University College Cork · IEUniversity College Dublin · IEUniversity of South Carolina · US

Funding

Breakthrough Cancer Research BCR-2018-07 PH-UCCHealth Research Board HRC/2007/13
6 · The paper itself

Abstract

purposeTo assess relationships between the Dietary Approaches to Stop Hypertension (DASH), Mediterranean Diet (MD), Dietary Inflammatory Index (DII

methodsThis was a cross-sectional study of 1862 men and women aged 46-73 years, randomly selected from a large primary care centre in Ireland. DASH, MD, DII and E-DII scores were derived from validated food frequency questionnaires. Correlation and multivariate-adjusted linear regression analyses with correction for multiple testing were performed to examine dietary score relationships with biomarker concentrations.

resultsIn fully adjusted models, higher diet quality or a less pro-inflammatory diet was associated with lower concentrations of c-reactive protein, neutrophils (all dietary scores), complement component 3 [C3], interleukin 6 [IL-6], tumour necrosis factor-alpha [TNF-α], white blood cell count [WBC], the neutrophil-to-lymphocyte ratio [NLR] (DASH, DII and E-DII), monocytes (DASH and DII) and resistin (DII and E-DII). After accounting for multiple testing, relationships with C3 (DASH: β = - 2.079, p = .011 and DII: β = 2.521, p = .036), IL-6 (DASH: β = - 0.063, p = .011), TNF-α (DASH: β = - 0.027, p = .034), WBC (DASH: β = - 0.028, p = .001 and DII: β = 0.029, p = .02), neutrophils (DASH: β = - 0.041, p = .001; DII: β = 0.043, p = .007; E-DII: β = 0.029, p = .009) and the NLR (DASH: β = - 0.035, p = .011) persisted.

conclusionsBetter diet quality, determined by the DASH score, may be more closely associated with inflammatory biomarkers related to health in middle- to older-aged adults than the MD, DII and E-DII scores.

Indexed as

Interleukin-6Tumor Necrosis Factor-alphaAgedBiomarkersCross-Sectional StudiesDietFemaleHumansInflammationMaleMiddle AgedBiomarkersInterleukin-6Tumor Necrosis Factor-alphaBiomarkersChronicDietInflammationScores

Identifiers

PMID35511284
PMCPMC9464136
OpenAlexW4229019067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.