Evidence map›Paper›PMID 35511253›Full record

ArticleJMIR formative research2022

Automated Analysis of Drawing Process to Estimate Global Cognition in Older Adults: Preliminary International Validation on the US and Japan Data Sets.

Yasunori Yamada, Kaoru Shinkawa, Masatomo Kobayashi, Varsha D Badal, Danielle Glorioso, Ellen E Lee, Rebecca Daly, Camille Nebeker, Elizabeth W Twamley, Colin Depp and 5 more

Open access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Yasunori YamadaDigital Health, IBM Research, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3333-4368
Kaoru ShinkawaDigital Health, IBM Research, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3869-1922
Masatomo KobayashiDigital Health, IBM Research, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4397-8557
Varsha D BadalDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0001-7281-9136
Danielle GloriosoDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0003-1644-5031
Ellen E LeeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0002-2250-765X
Rebecca DalyDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0001-6352-9188
Camille NebekerDepartment of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0001-6819-1796
Elizabeth W TwamleyDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0002-8693-8782
Colin DeppDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0002-1841-6229
Miyuki NemotoDepartment of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.ORCID https://orcid.org/0000-0002-1969-5098
Kiyotaka NemotoDepartment of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.ORCID https://orcid.org/0000-0001-8623-9829
Ho-Cheol KimAI and Cognitive Software, IBM Almaden Research Center, San Jose, CA, United States.ORCID https://orcid.org/0000-0003-0464-4340
Tetsuaki AraiDepartment of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.ORCID https://orcid.org/0000-0003-4355-3900
Dilip V JesteDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States.ORCID https://orcid.org/0000-0002-1161-7351
University of California San Diego · USUniversity of Tsukuba · JPIBM Research - Tokyo · JP

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Inflammatory Mechanisms Linking Sleep Disturbances and Cognitive Deficits in Schizophrenia in Later LifeK23MH119375 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEE, ELLEN EUN-OK · 2019 to 2023
$1.0M
NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

backgroundWith the aging of populations worldwide, early detection of cognitive impairments has become a research and clinical priority, particularly to enable preventive intervention for dementia. Automated analysis of the drawing process has been studied as a promising means for lightweight, self-administered cognitive assessment. However, this approach has not been sufficiently tested for its applicability across populations.

objectiveThe aim of this study was to evaluate the applicability of automated analysis of the drawing process for estimating global cognition in community-dwelling older adults across populations in different nations.

methodsWe collected drawing data with a digital tablet, along with Montreal Cognitive Assessment (MoCA) scores for assessment of global cognition, from 92 community-dwelling older adults in the United States and Japan. We automatically extracted 6 drawing features that characterize the drawing process in terms of the drawing speed, pauses between drawings, pen pressure, and pen inclinations. We then investigated the association between the drawing features and MoCA scores through correlation and machine learning-based regression analyses.

resultsWe found that, with low MoCA scores, there tended to be higher variability in the drawing speed, a higher pause:drawing duration ratio, and lower variability in the pen's horizontal inclination in both the US and Japan data sets. A machine learning model that used drawing features to estimate MoCA scores demonstrated its capability to generalize from the US dataset to the Japan dataset (R

conclusionsThis study presents initial empirical evidence of the capability of automated analysis of the drawing process as an estimator of global cognition that is applicable across populations. Our results suggest that such automated analysis may enable the development of a practical tool for international use in self-administered, automated cognitive assessment.

Indexed as

behavior analysiscognitive impairmentdementiadigital biomarkersdigital healthmachine learningmotor controlmulticohortmultinationtablet

Identifiers

PMID35511253
PMCPMC9121219
OpenAlexW4229041866

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.