Evidence map›Paper›PMID 35511166›Full record

ArticleThe Plant cell2022

Plant telomere biology: The green solution to the end-replication problem.

Eugene V Shakirov, Julian J-L Chen, Dorothy E Shippen

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heterochromatin in plant meiosis.Nucleus (Austin, Tex.) · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Telomere Length Variation in Model Bryophytes.Plants (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Eugene V ShakirovDepartment of Biological Sciences, College of Science, Marshall University, Huntington, West Virginia 25701, USA.ORCID 0000-0003-2689-7410
Julian J-L ChenSchool of Molecular Sciences, Arizona State University, Tempe, Arizona 85287, USA.ORCID 0000-0002-7253-2722
Dorothy E ShippenDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843-2128, USA.ORCID 0000-0003-0562-2047
Arizona State University · USMarshall University · USTexas A&M University · US

Funding

Telomere Structure and Function in ArabidopsisR01GM065383 · NIGMS · TEXAS A&M UNIVERSITY SYSTEM · PI SHIPPEN, DOROTHY · 2002 to 2023
$6.8M
Genetic and epigenetic architecture of natural telomere length variationR01GM127402 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI SHAKIROV, EUGENE V · 2018 to 2025
$2.4M
NIGMS NIH HHS R01 GM065383NIGMS NIH HHS R01 GM127402
6 · The paper itself

Abstract

Telomere maintenance is a fundamental cellular process conserved across all eukaryotic lineages. Although plants and animals diverged over 1.5 billion years ago, lessons learned from plants continue to push the boundaries of science, revealing detailed molecular mechanisms in telomere biology with broad implications for human health, aging biology, and stress responses. Recent studies of plant telomeres have unveiled unexpected divergence in telomere sequence and architecture, and the proteins that engage telomeric DNA and telomerase. The discovery of telomerase RNA components in the plant kingdom and some algae groups revealed new insight into the divergent evolution and the universal core of telomerase across major eukaryotic kingdoms. In addition, resources cataloging the abundant natural variation in Arabidopsis thaliana, maize (Zea mays), and other plants are providing unparalleled opportunities to understand the genetic networks that govern telomere length polymorphism and, as a result, are uncovering unanticipated crosstalk between telomeres, environmental factors, organismal fitness, and plant physiology. Here we recap current advances in plant telomere biology and put this field in perspective relative to telomere and telomerase research in other eukaryotic lineages.

Indexed as

ArabidopsisTelomeraseAnimalsBiologyPlantsTelomereTelomerase

Identifiers

PMID35511166
PMCPMC9252485
OpenAlexW4226189924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.