Evidence map›Paper›PMID 35510877›Full record

ArticleRNA biology2022

CNOT1 regulates circadian behaviour through

Haytham Mohamed Aly Mohamed, Akinori Takahashi, Saori Nishijima, Shungo Adachi, Iori Murai, Hitoshi Okamura, Tadashi Yamamoto

Open access · goldAbstract read
In one paragraph

Article in RNA biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Haytham Mohamed Aly MohamedCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.ORCID 0000-0003-0056-8141
Akinori TakahashiCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Saori NishijimaCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Shungo AdachiMolecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.ORCID 0000-0001-5232-411X
Iori MuraiLaboratory of Molecular Brain Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Hitoshi OkamuraLaboratory of Molecular Brain Science, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.ORCID 0000-0002-3013-4881
Tadashi YamamotoCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.ORCID 0000-0002-5938-9378
Okinawa Institute of Science and Technology Graduate University · JPKyoto University · JPNational Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian clocks are an endogenous internal timekeeping mechanism that drives the rhythmic expression of genes, controlling the 24 h oscillatory pattern in behaviour and physiology. It has been recently shown that post-transcriptional mechanisms are essential for controlling rhythmic gene expression. Controlling the stability of mRNA through poly(A) tail length modulation is one such mechanism. In this study, we show that

Indexed as

Circadian RhythmPeriod Circadian ProteinsAnimalsMammalsMiceRNA, MessengerRNA StabilitySuprachiasmatic NucleusTranscription FactorsCnot1 protein, mousePer2 protein, mousePeriod Circadian ProteinsRNA, MessengerTranscription Factorscircadian rhythmDeadenylationmRNA decaypost-transcriptional regulation

Identifiers

PMID35510877
PMCPMC9090297
OpenAlexW4229002932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.