Evidence map›Paper›PMID 35510678›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2022

Neutron Diffraction Study of Indole Solvation in Deep Eutectic Systems of Choline Chloride, Malic Acid, and Water.

Oliver S Hammond, Ria Atri, Daniel T Bowron, Karen J Edler

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Oliver S HammondCentre for Sustainable Chemical Technologies and Department of Chemistry, University of Bath Claverton Down, Bath, BA2 7AY, U.K.ORCID http://orcid.org/0000-0002-5612-9343
Ria AtriCentre for Sustainable Chemical Technologies and Department of Chemical Engineering, University of Bath Claverton Down, Bath, BA2 7AY, U.K.ORCID http://orcid.org/0000-0002-9439-8982
Daniel T BowronISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Didcot, OX11 0QX, U.K.ORCID http://orcid.org/0000-0002-4557-1929
Karen J EdlerCentre for Sustainable Chemical Technologies and Department of Chemistry, University of Bath Claverton Down, Bath, BA2 7AY, U.K.ORCID http://orcid.org/0000-0001-5822-0127
University of Bath · GBScience and Technology Facilities Council · GBStockholm University · SE

Funding

Engineering and Physical Sciences Research Council EP/L016354/1
6 · The paper itself

Abstract

Deep eutectic systems are currently under intense investigation to replace traditional organic solvents in a range of syntheses. Here, indole in choline chloride-malic acid deep eutectic solvent (DES) was studied as a function of water content, to identify solute interactions with the DES which affect heterocycle reactivity and selectivity, and as a proxy for biomolecule solvation. Empirical Potential Structure Refinement models of neutron diffraction data showed [Cholinium]

Indexed as

CholineWaterIndolesMalatesNeutron DiffractionCholineIndolesMalatesmalic acidWaterdeep eutectic solventsgreen chemistryheterocyclesneutron diffractionpi interactions

Identifiers

PMID35510678
PMCPMC9400976
OpenAlexW4228997405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.