Evidence map›Paper›PMID 35510660›Full record

ArticleBasic & clinical pharmacology & toxicology2022

Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells.

Yufang Deng, Ee Von Moo, Claudia Victoria Pérez Almería, Patrick R Gentry, Line Vedel, Jesper M Mathiesen, Hans Bräuner-Osborne

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Basic & clinical pharmacology & toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Yufang DengDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0002-0104-1344
Ee Von MooDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0003-2629-9779
Claudia Victoria Pérez AlmeríaDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0002-7312-8529
Patrick R GentryDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0003-0670-6648
Line VedelDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.
Jesper M MathiesenDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0003-4251-4416
Hans Bräuner-OsborneDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen.ORCID https://orcid.org/0000-0001-9495-7388
University of Copenhagen · DK

Funding

Carlsbergfondet CF20-0248China Scholarship Council 201907940002Horizon 2020 Framework Programme 846827Novo Nordisk Fonden NNF17OC0028412Novo Nordisk Fonden NNF19OC0057730
6 · The paper itself

Abstract

The GPR15 receptor is a G protein-coupled receptor (GPCR), which is activated by an endogenous peptide GPR15L(25-81) and a C-terminal peptide fragment GPR15L(71-81). GPR15 signals through the G

Indexed as

GTP-Binding ProteinsSignal TransductionAnimalsMammalsPertussis ToxinReceptors, G-Protein-CoupledGTP-Binding ProteinsPertussis ToxinReceptors, G-Protein-CoupledBRETGPR15Gα proteinsecond messengersignalling

Identifiers

PMID35510660
PMCPMC9539578
OpenAlexW4229013775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.