Evidence map›Paper›PMID 35510248›Full record

ArticleFrontiers in medicine2022

Bioinformatic Analyzes of the Association Between Upregulated Expression of

Huan Chen, Liyun Zhao, Jiaqiang Liu, Housheng Zhou, Xi Wang, Xiaoling Fang, Xiaomeng Xia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Frontiers in oncology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Huan ChenDepartment of Obstetrics and Gynecology, The Second XIANGYA Hospital of Central South University, Changsha, China.
Liyun ZhaoDepartment of Obstetrics and Gynecology, The Second XIANGYA Hospital of Central South University, Changsha, China.
Jiaqiang LiuLaboratory Medicine Center, Zhu Zhou Hospital Affiliated to Xiangya School of Medicine, Central South University (CSU), Zhuzhou, China.
Housheng ZhouDepartment of Obstetrics and Gynecology, Zhu Zhou Hospital Affiliated to Xiangya School of Medicine, CSU, Zhuzhou, China.
Xi WangDepartment of Obstetrics and Gynecology, The Second XIANGYA Hospital of Central South University, Changsha, China.
Xiaoling FangDepartment of Obstetrics and Gynecology, The Second XIANGYA Hospital of Central South University, Changsha, China.
Xiaomeng XiaDepartment of Obstetrics and Gynecology, The Second XIANGYA Hospital of Central South University, Changsha, China.
Central South University · CNZhuzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, cervical cancer (CC) is the most common malignant tumor of the female reproductive system and its incidence is only second after breast cancer. Although screening and advanced treatment strategies have improved the rates of survival, some patients with CC still die due to metastasis and drug resistance. It is considered that cancer is driven by somatic mutations, such as single nucleotide, small insertions/deletions, copy number, and structural variations, as well as epigenetic changes. Previous studies have shown that cervical intraepithelial neoplasia is associated with copy number variants (CNVs) and/or mutations in cancer-related genes. Further, CC is also related to genetic mutations. The present study analyzed the data on somatic mutations of cervical squamous cell carcinoma (CESC) in the Cancer Genome Atlas database. It was evident that the Apolipoprotein B mRNA editing enzyme-catalyzed polypeptide-like (

Indexed as

APOBECcervical cancerFLGJUNmutation

Identifiers

PMID35510248
PMCPMC9058067
OpenAlexW4224087720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.