Evidence map›Paper›PMID 35510238›Full record

ArticleToxicology research2022

PGI score: prospective validation and correlation with SOFA, SAPS-II, and APACHE-II scores for predicting outcomes in acute aluminum phosphide poisoning.

A K Pannu, L Jhuria, A Bhalla, N Sharma

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Article in Toxicology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

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12citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

A K PannuDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.ORCID https://orcid.org/0000-0002-4476-3478
L JhuriaDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
A BhallaDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
N SharmaDepartment of Internal Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: We recently derived a simplified 3-point PGI score (representing blood pH < 7.25, Glasgow coma scale [GCS] score < 13, and impaired systolic blood pressure [SBP] < 90 mm Hg), which accurately predicted in-hospital case fatality ratio (CFR) in acute aluminum phosphide poisoning. The present study aimed to validate the PGI score and compare it with Acute Physiologic Assessment and Chronic Health Evaluation (APACHE) II score, Sequential Organ Failure Assessment score (SOFA), and Simplified Acute Physiology Score (SAPS) II scores. Patients and Methods: We performed a prospective cohort study in adult patients with aluminum phosphide ingestion admitted in PGIMER, Chandigarh (India), from April 2013 to August 2014. A univariant analysis detected the association of various baseline variables with CFR. Correlation of the PGI score with SOFA, SAPS-II, and APACHE-II scores was performed using Spearman's correlation ( Results: Seventy-six patients were enrolled (mean age, 28.3 years; 41 males). CFR was 60.5%. PGI score variables-pH, GCS, and impaired SBP predicted CFR ( Conclusion: The PGI score is a validated toxidrome-specific and simplified risk-stratification tool. Validation in other populations is warranted to confirm its routine use.

Indexed as

aluminum phosphideAPACHE-IIcase fatality ratioPGIpredicting toolprognosisSAPS-IIscoring systemSOFA

Identifiers

PMID35510238
PMCPMC9052320

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.