Evidence map›Paper›PMID 35510176›Full record

ArticleBioactive materials2023

Biomimetic manganese-based theranostic nanoplatform for cancer multimodal imaging and twofold immunotherapy.

Yuyue Zhao, Yuanwei Pan, Kelong Zou, Zhou Lan, Guowang Cheng, Qiuying Mai, Hao Cui, Qianfang Meng, Tongkai Chen, Lang Rao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Early Transition Metal-Based Antitumor Complexes.Chemistry, an Asian journal · 2026
    Review
  6. Review
  7. Review
  8. Mitochondria-targeted MXene@MnOBioactive materials · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Embracing cancer immunotherapy with manganese particles.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Dual-modality immune nano-activator harnessing MnJournal of nanobiotechnology · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Yuyue ZhaoStomatological Hospital, Southern Medical University, Guangzhou, 510280, China.
Yuanwei PanInstitute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Kelong ZouStomatological Hospital, Southern Medical University, Guangzhou, 510280, China.
Zhou LanStomatological Hospital, Southern Medical University, Guangzhou, 510280, China.
Guowang ChengScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Qiuying MaiScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Hao CuiStomatological Hospital, Southern Medical University, Guangzhou, 510280, China.
Qianfang MengInstitute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Tongkai ChenScience and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Lang RaoInstitute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen, 518132, China.
Limin MaMedical Research Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China.
Guangtao YuStomatological Hospital, Southern Medical University, Guangzhou, 510280, China.
Southern Medical University · CNGuangzhou University of Chinese Medicine · CNShenzhen Bay Laboratory · CNGuangdong Academy of Medical Sciences · CNNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited clinical response and serious side effect have been challenging in cancer immunotherapy resulting from immunosuppressive tumor microenvironment (TME) and inferior drug targeting. Herein, an active targeting TME nanoplatform capable of revising the immunosuppressive TME microenvironment is designed. Briefly, gold nanorods (GNRs) are covered with silica dioxide (SiO

Indexed as

BiomimeticCancer imagingImmunotherapyManganese ionsThe second near-infrared window

Identifiers

PMID35510176
PMCPMC9048124
OpenAlexW4224214956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.