ReviewOxidative medicine and cellular longevity2022
Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects.
RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph
Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 37 papers.
0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 72 citations in OpenAlex.
- Bergapten protects chondrocytes against sodium nitroprusside-induced dedifferentiation and apoptosis through NF-κB and p38 signaling pathway.In vitro cellular & developmental biology. Animal · 2025Article
- Fabrication of bergapten loaded microneedle patch and assessment of its anti-arthritic potential against complete Freund's adjuvant induced arthritis in Wistar rat.Inflammopharmacology · 2025Article
- Phytochemical Profiling and Anti-Inflammatory Effects of Aerial and Underground Parts ofFood science & nutrition · 2025Article
- Unveiling the therapeutic potential of HZQYF: exploring the inhibitory impact of a clinical herbal formula on gastric cancer through network pharmacology and transcript analysis.BMC complementary medicine and therapies · 2025Article
- Discovery of potent anti-toxoplasmosis drugs from secondary metabolites in Citrus limon (lemon) leaves, supported in-silico study.Scientific reports · 2025Article
- Dried Apricot Polyphenols Suppress the Growth of A549 Human Lung Adenocarcinoma Cells by Inducing Apoptosis via a Mitochondrial-Dependent Pathway.Foods (Basel, Switzerland) · 2025Article
- Exploring the Therapeutic Role of Natural Products in Allergic Rhinitis Based on Pathophysiology and Signaling Pathways.Journal of asthma and allergy · 2025Review
- Exploring acupuncture as a therapeutic approach for tic disorders: a review of current understanding and potential benefits.Frontiers in neurology · 2025Review
- Ripening-dependent changes in antioxidant activities and un-targeted phytochemical fingerprinting of mango (Journal of nutritional science · 2025Article
- Bergapten enhances mitophagy to regulate intestinal barrier and Th17/Treg balance in mice with Crohn's disease-like colitis via PPARγ/NF-κB signaling pathway.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Article
- Bioassay-Guided Fractionation ofPlants (Basel, Switzerland) · 2024Article
- Angelica dahurica extract and its effective component bergapten alleviated hepatic fibrosis by activating FXR signaling pathway.Journal of natural medicines · 2024Article
- Retracted: Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects.Oxidative medicine and cellular longevity · 2024Article
- System Pharmacological Approach to Investigate and Validate Multitargeted and Therapeutic Effect of Furocoumarins ofAdvances in pharmacological and pharmaceutical sciences · 2024Article
- Evaluation of the Biological Effect of Non-UV-Activated Bergapten on Selected Human Tumor Cells and the Insight into the Molecular Mechanism of Its Action.International journal of molecular sciences · 2023Article
- Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy.Cell communication and signaling : CCS · 2023Review
- Natural antioxidants from some fruits, seeds, foods, natural products, and associated health benefits: An update.Food science & nutrition · 2023Review
- A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeonia emodi Wall. ex Royle: current landscape and future perspectives.Chinese medicine · 2023Review
- Naringenin and Hesperidin as Promising Alternatives for Prevention and Co-Adjuvant Therapy for Breast Cancer.Antioxidants (Basel, Switzerland) · 2023Review
Corrections and comments
- Retraction · 2024-01-09Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · Computer-Aided Content or Computer-Generated Content · Unreliable Results and/or Conclusions ·
- Retracted
Authors and funding
22 authors at 17 institutions in 11 countries.
Maria Magdalena Quetglas-LlabrésResearch Group in Community Nutrition and Oxidative Stress, University of the Balearic Islands and Health Research Institute of Balearic Islands (IdISBa), 07122 Palma de Mallorca, Spain.
Cristina QuispeFacultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile.ORCID https://orcid.org/0000-0002-2090-3288
Jesús Herrera-BravoDepartamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomas, Chile.ORCID https://orcid.org/0000-0003-0739-7920
Marcelo D CatarinoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Olívia R PereiraCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Susana M CardosoLAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Kamal DuaDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Ultimo NSW 2007, Australia.
Dinesh Kumar ChellappanDepartment of Life Sciences, School of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia.ORCID https://orcid.org/0000-0001-5567-6663
Kavita PabrejaSchool of Pharmaceutical Sciences, Lovely Professional University, Jalandhar, Delhi G.T. Road (NH-1), Phagwara, 144411 Punjab, India.
Saurabh SatijaSchool of Pharmaceutical Sciences, Lovely Professional University, Jalandhar, Delhi G.T. Road (NH-1), Phagwara, 144411 Punjab, India.
Meenu MehtaSchool of Pharmaceutical Sciences, Lovely Professional University, Jalandhar, Delhi G.T. Road (NH-1), Phagwara, 144411 Punjab, India.
Antoni SuredaResearch Group in Community Nutrition and Oxidative Stress, University of the Balearic Islands and Health Research Institute of Balearic Islands (IdISBa), 07122 Palma de Mallorca, Spain.ORCID https://orcid.org/0000-0001-8656-6838
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, And Centre for Healthy Living, University of Concepción, 4070386 Concepción, Chile.ORCID https://orcid.org/0000-0003-3183-7623
Dinara SatmbekovaHigh School of Medicine, Al-Farabi Kazakh National University, Almaty, Kazakhstan.ORCID https://orcid.org/0000-0003-1087-3932
Balakyz YeskaliyevaFaculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, Kazakhstan.ORCID https://orcid.org/0000-0002-1745-2738
Javad Sharifi-RadFacultad de Medicina, Universidad del Azuay, Cuenca, Ecuador.ORCID https://orcid.org/0000-0002-7301-8151
Naeem RasoolDepartment Pharmacology and Toxicology, University of Veterinary and Animals Science, Lahore, Pakistan.
Monica ButnariuBanat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Timisoara, Romania.ORCID https://orcid.org/0000-0002-2032-5000
Iulia Cristina BagiuVictor Babes University of Medicine and Pharmacy of Timisoara Department of Microbiology, Timisoara, Romania.ORCID https://orcid.org/0000-0003-3099-8249
Radu Vasile BagiuVictor Babes University of Medicine and Pharmacy of Timisoara Department of Microbiology, Timisoara, Romania.ORCID https://orcid.org/0000-0002-1528-5630
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.ORCID https://orcid.org/0000-0003-4174-4586
Lovely Professional University · INAl-Farabi Kazakh National University · KZRede de Química e Tecnologia · PTVictor Babeș University of Medicine and Pharmacy Timișoara · ROArturo Prat University · CLHealth Research Institute of the Balearic Islands · ESIMU University · MYInstituto de Salud Carlos III · ESPolytechnic Institute of Bragança · PTQueen Elizabeth Hospital · CNUniversidad de La Frontera · CLUniversidad del Azuay · ECUniversity of Concepción · CLUniversity of Medicine and Pharmacy of Craiova · ROUniversity of Technology Sydney · AUUniversity of Veterinary and Animal Sciences · PKUnivesity of Life Science "King Mihai I" from Timisoara · RO
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bergapten (BP) or 5-methoxypsoralen (5-MOP) is a furocoumarin compound mainly found in bergamot essential oil but also in other citrus essential oils and grapefruit juice. This compound presents antibacterial, anti-inflammatory, hypolipemic, and anticancer effects and is successfully used as a photosensitizing agent. The present review focuses on the research evidence related to the therapeutic properties of bergapten collected in recent years. Many preclinical and
Indexed as
MethoxsalenOils, Volatile5-MethoxypsoralenHumansPhotosensitizing AgentsPlant ExtractsUltraviolet Rays5-MethoxypsoralenMethoxsalenOils, VolatilePhotosensitizing AgentsPlant Extracts
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.