Evidence map›Paper›PMID 35509770›Full record

ArticleTherapeutic advances in neurological disorders2022

Both subthalamic and pallidal deep brain stimulation are effective for

Ye Liu, Qingping Zhang, Jun Wang, Jiyuan Liu, Wuyang Yang, Xuejing Yan, Yi Ouyang, Haibo Yang

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in neurological disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Phenotypes in children withFrontiers in pediatrics · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ye LiuDepartment of Neurology, The First Hospital of China Medical University, Shenyang, China.
Qingping ZhangDepartment of Pediatrics, Peking University First Hospital, Beijing, China.
Jun WangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Jiyuan LiuDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Wuyang YangDepartment of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Xuejing YanDepartment of Neurology, The First Hospital of China Medical University, Shenyang, China.
Yi OuyangDepartment of Neurology, The First Hospital of China Medical University, Shenyang 110001, Liaoning, China.ORCID https://orcid.org/0000-0002-6815-6058
Haibo YangDepartment of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
First Hospital of China Medical University · CNPeking University · CNJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mutations in the G-protein subunit alpha o1 ( Objective: The objective of this study was to explore diagnostic and therapeutic strategies for Methods: This study describes the cases of three Chinese patients who had shown severe and progressive dystonia in the absence of epilepsy since early childhood. We performed genetic analyses in these patients. Patients 1 and 2 underwent globus pallidus internus (GPi) deep brain stimulation (DBS) implantation, and Patient 3 underwent subthalamic nucleus (STN) DBS implantation. In addition, on the basis of a literature review, we summarized and discussed the clinical characteristics and outcomes after DBS surgery for all reported patients with Results: Whole-exome sequencing (WES) analysis revealed Conclusion: DBS is effective in ameliorating motor symptoms in patients with

Indexed as

deep brain stimulationde novo variantdystoniaGNAO1-associated movement disorderswhole-exome sequencing analysis

Identifiers

PMID35509770
PMCPMC9058460
OpenAlexW4226467729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.