ArticleCureus2022
Tumor-to-Tumor Metastasis of Renal Cell Carcinoma to a Follicular Variant of Papillary Thyroid Carcinoma: A Case Report and Literature Review.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Clear Cell Renal Cell Carcinoma Metastasis to the Thyroid: A Narrative Review of the Literature.Cancers · 2025Review
- Metastasis of clear cell renal cell carcinoma to hyalinizing trabecular tumor of the thyroid: A case report.Oncology letters · 2025Article
- Case Report: Tumor-to-tumor metastasis: a rare case of prostate adenocarcinoma metastasis to lung squamous cell carcinoma in a patient with multiple primary malignancies.Frontiers in oncology · 2025Article
- Unraveling Tumor-to-Tumor Metastasis: Insights into Pathogenesis, Diagnostic Challenges, and Treatment Modalities.Biologics : targets & therapy · 2025Review
- A Rare Case of Tumor-to-Tumor Metastasis: Renal Cell Carcinoma Metastasis to Papillary Thyroid Carcinoma.JCEM case reports · 2024Article
- Tumor-to-Tumor Metastasis of Lung Cancer to Kidney Cancer: A Review of the Literature and Our Experience.Diagnostics (Basel, Switzerland) · 2024Review
- Case report: Report of a rare encounter: metastasis of renal cell carcinoma to the thyroid.Frontiers in oncology · 2024Article
- Tumor-to-tumor spread: a case report and literature review of renal cell carcinoma metastasis into thyroid cancer.World journal of surgical oncology · 2023Review
- Metastatic Disease to a Concurrent Thyroid Neoplasm: A Case Series and Review of the Literature.Head and neck pathology · 2023Review
- Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation.Clinics and practice · 2023Article
- Case Report: Tumor-to-tumor metastasis with prostate cancer metastatic to lung cancer: the first reported case.Frontiers in oncology · 2023Article
- Article
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Authors and funding
2 authors.
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Abstract
Renal cell carcinoma (RCC) is the most common renal malignancy. It has a variable clinical course with metastasis to unusual sites occurring months to years after the initial diagnosis. However, metastasis can also be the first presentation of RCC. Although relatively uncommon, the thyroid gland is the most common location for RCC metastasis in the head and neck region. Tumor-to-tumor metastasis is an exceedingly rare occurrence. Only 10 cases were reported of RCC metastasis to primary thyroid neoplasms. We present a case of clear cell RCC metastasizing to a follicular of variant papillary thyroid carcinoma (FVPTC) 14 years after the initial diagnosis of RCC. A review of similar reported cases revealed that the most common primary thyroid recipient of tumor-to-tumor metastasis of RCC was FVPTC. The rich lymphovascular network in FVPTC compared to other thyroid tumors, which may promote the deposition of metastatic tumor cells, might explain this predilection. Careful review of the clinical and radiological findings and checking for any history of malignancy when examining thyroid nodules is important for guiding further studies. Performing a targeted panel of immunohistochemical stains for any suspicious areas is also essential for the diagnosis of such unusual cases.
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