Evidence map›Paper›PMID 35509513›Full record

ArticleFrontiers in public health2022

Evaluation of Essential and Toxic Elements in the Blood of 0-14-Year-Old Children in Hunan, China From 2013 to 2019: A Retrospective Analysis.

Shan Tan, Yang Yang, Zhiheng Chen, Lingling Zhao, Zuocheng Yang, Hongmei Dai, Wei He, Mei Jiang, Yanhua Yao, Ke Huang and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Shan TanDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Yang YangDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Zhiheng ChenDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Lingling ZhaoDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Zuocheng YangDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Hongmei DaiDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Wei HeDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Mei JiangDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Yanhua YaoDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Ke HuangDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Liu LiDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Pengfei ZhuDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Shasha XuDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Mingyi ZhaoDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Minghua YangDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, China.
Third Xiangya Hospital · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim was to investigate the distribution and correlation of Ca, Mg, Zn, Cu, Fe, Pb, and Cd in the blood of children aged 0-14 years in Hunan, China, which may serve to provide a basis for clinical guidance on child health. Study Design: A retrospective analysis was carried out. Concentrations of all elements were determined by atomic absorption spectrophotometry. Distributions were analyzed and compared among different age, sex, and year groups by the Kruskal-Wallis test, the chi-square test, and the Fisher's exact test. Spearman's rank correlation coefficient was used to evaluate the association between every pair of elements. Results: A total of 46,951 children were involved in this study from 2013 to 2019. The median blood levels of elements were 13.51 μmol/L (Cu), 58.69 μmol/L (Zn), 1.70 mmol/L (Ca), 1.40 mmol/L (Mg), 7.46 mmol/L (Fe), 35.00 μg/L (Pb), and 1.00 μg/L (Cd). Girls had a higher level of Ca and lower levels of Pb and Cd than boys. Cu and Ca showed an upward trend, and Mg and Pb showed a downward trend by year. Zn and Fe increased and Ca decreased significantly with age. The deficiency rates of Fe and Zn decreased significantly by year, while Ca and Cu increased significantly by year. Cd exposure in this area was relatively low. Conclusion: Most children had normal levels of the essential elements Ca, Cu, and Mg and the toxic elements Pb and Cd. Severe deficiencies in Zn and Fe were observed in the relatively younger children but improved with age. Persistent efforts in reducing Pb exposure might still be needed.

Indexed as

CopperZincAdolescentCadmiumChildChild, PreschoolChinaFemaleHumansInfantInfant, NewbornLeadMaleRetrospective StudiesCadmiumCopperLeadZincchildrenessential elementsHunannutritiontoxic elements

Identifiers

PMID35509513
PMCPMC9058121
OpenAlexW4223891621

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.