ArticleChem2021
Synthesis of
Article in Chem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- Synthesis and properties ofChemical science · 2026Review
- Charting New Territory: Systematic Evaluation of the Drug Potential ofJournal of medicinal chemistry · 2026Article
- Article
- Bench-stable azidodifluoromethyl imidazolium reagents unlock the synthetic potential of carbonimidic difluorides.Nature communications · 2025Article
- Access to N-Monofluoromethylated (Thio)Carbamates, Formamides, Alkynamides, and Related Derivatives.Angewandte Chemie (International ed. in English) · 2025Article
- Desulfurizative Fluorination of N-CFAngewandte Chemie (International ed. in English) · 2025Article
- Direct synthesis of N-trifluoromethyl amides via photocatalytic trifluoromethylamidation.Nature communications · 2025Article
- A mild and practical approach to N-CFNature communications · 2025Article
- Preparation, separation and storage of N-monofluoromethyl amides and carbamates.Nature chemistry · 2025Article
- General strategy for the synthesis of N-monofluoromethyl amides.Nature chemistry · 2025Article
- Recent advances in synthetic approaches for bioactive cinnamic acid derivatives.Beilstein journal of organic chemistry · 2025Review
- N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides.Nature communications · 2024Article
- Access toJournal of the American Chemical Society · 2024Article
- Novel N(SCFChemical science · 2023Article
- Access to N-CFAngewandte Chemie (International ed. in English) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Found in biomolecules, pharmaceuticals, and agrochemicals, amide-containing molecules are ubiquitous in nature, and their derivatization represents a significant methodological goal in fluorine chemistry. Trifluoromethyl amides have emerged as important functional groups frequently found in pharmaceutical compounds. To date, there is no strategy for synthesizing
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.