Evidence map›Paper›PMID 35509425›Full record

ReviewTherapeutic advances in gastroenterology2022

Application of artificial intelligence in diagnosis of pancreatic malignancies by endoscopic ultrasound: a systemic review.

Hemant Goyal, Syed Ali Amir Sherazi, Shweta Gupta, Abhilash Perisetti, Ikechukwu Achebe, Aman Ali, Benjamin Tharian, Nirav Thosani, Neil R Sharma

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Therapeutic advances in gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07381192 recruitingnot on this mapstarted 2025, after this paper: background citation

An Artificial Intelligence System for Multimodal, Multi-class Diagnosing Solid Pancreatic Lesions Based on Endoscopic Ultrasound

Typeobservational_patient_registrySponsorQilu Hospital of Shandong UniversityRan2025 to 2028Enrolled383ConditionsEndoscopic Ultrasound (EUS), Solid Pancreatic LesionArmsiEUS-SPL(intelligent endoscopic ultrasound system-pancreatic solid lesion)
NCT07543263 recruitingnot on this mapstarted 2026, after this paper: background citation

An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography

TypeobservationalSponsorQilu Hospital of Shandong UniversityRan2026 to 2028Enrolled176ConditionsPancreatic Cystic Lesion (PCL)ArmsiEUS-PCL(intelligent endoscopic ultrasound system- pancreatic cystic lesion)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Hemant GoyalThe Wright Center for Graduate Medical Education, 501 S. Washington Avenue, Scranton, PA 18503, USA.ORCID https://orcid.org/0000-0002-9433-9042
Syed Ali Amir SheraziDepartment of Medicine, John H. Stroger J.r Hospital of Cook County, Chicago, IL, USA.
Shweta GuptaDivision of Hematology-Oncology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, USA.
Abhilash PerisettiAdvanced Interventional Oncology and Surgical Endoscopy, Parkview Cancer Institute, Parkview Health, Fort Wayne, IN, USA.
Ikechukwu AchebeDepartment of Medicine, John H. Stroger J.r Hospital of Cook County, Chicago, IL, USA.
Aman AliCommonwealth Medical College, Scranton, PA, USA; Wilkes Barre General Hospital, Wilkes-Barre, PA, USA; Digestive Care Associates, Kingston, PA, USA.
Benjamin TharianUniversity of Arkansas for Medical Sciences, Little Rock, AR, USA.
Nirav ThosaniCenter for Interventional Gastroenterology at UTHealth (iGUT), Houston, TX, USADivision of Gastroenterology, Hepatology & Nutrition, McGovern Medical School, UTHealth, Houston, TX, USA.
Neil R SharmaDivision of interventional Oncology & Surgical Endoscopy (IOSE), Parkview cancer Institute, Fort Wayne, IN, USAIndiana University School of Medicine, Fort Wayne, IN, USA.
John H. Stroger, Jr. Hospital of Cook County · USParkview Health · USDigestive Care (United States) · USThe University of Texas Health Science Center at Houston · USThe Wright Center for Graduate Medical Education · USUniversity of Arkansas for Medical Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pancreatic cancer (PC) is a highly fatal malignancy with a global overall 5-year survival of under 10%. Screening of PC is not recommended outside of clinical trials. Endoscopic ultrasonography (EUS) is a very sensitive test to identify PC but lacks specificity and is operator-dependent, especially in the presence of chronic pancreatitis (CP). Artificial Intelligence (AI) is a growing field with a wide range of applications to augment the currently available modalities. This study was undertaken to study the effectiveness of AI with EUS in the diagnosis of PC. Methods: Studies from MEDLINE and EMBASE databases reporting the AI performance applied to EUS imaging for recognizing PC. Data were analyzed using descriptive statistics. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used to assess the quality of the included studies. Results: A total of 11 articles reported the role of EUS in the diagnosis of PC. The overall accuracy, sensitivity, and specificity of AI in recognizing PC were 80-97.5%, 83-100%, and 50-99%, respectively, with corresponding positive predictive value (PPV) and negative predictive value (NPV) of 75-99% and 57-100%, respectively. Types of AI studied were artificial neural networks (ANNs), convolutional neural networks (CNN), and support vector machine (SVM). Seven studies using other than basic ANN reported a sensitivity and specificity of 88-96% and 83-94% to differentiate PC from CP. Two studies using SVM reported a 94-96% sensitivity, 93%-99% specificity, and 94-98% accuracy to diagnose PC from CP. The reported sensitivity and specificity of detection of malignant from benign Intraductal Papillary Mucinous Neoplasms (IPMNs) was 96% and 92%, respectively. Conclusion: AI reported a high sensitivity with high specificity and accuracy to diagnose PC, differentiate PC from CP, and differentiate benign from malignant IPMN when used with EUS.

Indexed as

artificial intelligenceartificial neural networkconvolutional neural networkendoscopic ultrasonographypancreatic cancersupport vector machine

Identifiers

PMID35509425
PMCPMC9058356
OpenAlexW4225789892

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.