Evidence map›Paper›PMID 35509416›Full record

ArticleHealth science reports2022

Body mass index trajectories and associations with cognitive decline in people with Lewy body dementia and Alzheimer's disease.

Miguel G Borda, Alberto Jaramillo-Jimenez, Lasse M Giil, Diego A Tovar-Rios, Hogne Soennesyn, Dag Aarsland

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Intrinsic capacity in Lewy body dementia: a review.The Journal of frailty & aging · 2025
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Miguel G BordaCentre for Age-Related Medicine (SESAM) Stavanger University Hospital Stavanger Norway.ORCID https://orcid.org/0000-0001-5832-0603
Alberto Jaramillo-JimenezCentre for Age-Related Medicine (SESAM) Stavanger University Hospital Stavanger Norway.ORCID 0000-0001-5374-6410
Lasse M GiilDepartment of Internal Medicine Haraldsplass Deaconess Hospital Bergen Norway.
Diego A Tovar-RiosCentre for Age-Related Medicine (SESAM) Stavanger University Hospital Stavanger Norway.
Hogne SoennesynCentre for Age-Related Medicine (SESAM) Stavanger University Hospital Stavanger Norway.
Dag AarslandCentre for Age-Related Medicine (SESAM) Stavanger University Hospital Stavanger Norway.
Stavanger University Hospital · NOHaraldsplass Diakonale Sykehus · NOKing's College London · GBPontificia Universidad Javeriana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: In older adults with dementia, low body mass index (BMI) is associated with higher mortality and other adverse health outcomes. BMI or nutritional status trajectories from diagnosis have not yet been well described in dementia, especially in people with Lewy body dementia (LBD); a group that has a poorer prognosis. With this study, we aimed to evaluate the BMI trajectory in people diagnosed with mild LBD and Alzheimer's disease (AD). Methods: The Dementia Study of Western Norway is a cohort study with annual assessments. Five-year measurements of BMI from 196 patients (LBD = 85 and AD = 111) diagnosed with mild dementia were analyzed using adjusted linear mixed-effects models. Results: There were no differences between LBD and AD in baseline BMI, age, or mini-mental status examination (MMSE). During the follow-up, we observed a significant decrease in BMI in the LBD group across the study period (estimation [Est.]: -0.63, SE: 0.14; Conclusion: In LBD, BMI significantly decreased with disease progression. In addition, low cognitive performance was associated with a reduction in BMI. These results highlight the importance of BMI evaluation in people with dementia, particularly patients diagnosed with LBD, and suggest that patients with LBD could be targeted for dietary intervention to maintain body weight.

Indexed as

Alzheimer's diseasebody mass indexdementiaLewy body dementiamalnutrition

Identifiers

PMID35509416
PMCPMC9060322
OpenAlexW4225279695

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.