Evidence map›Paper›PMID 35509400›Full record

ArticleHealth science reports2022

Hematological findings in adult patients with SARS CoV-2 infection at Tygerberg Hospital Cape Town South Africa.

Ibtisam Abdullah, Helena M Cornelissen, Ernest Musekwa, Annalise Zemlin, Thumeka Jalavu, Nomusa Mashigo, Carissa Chetty, Nokwazi Nkosi, Zivanai C Chapanduka

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ibtisam AbdullahDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
Helena M CornelissenDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
Ernest MusekwaDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
Annalise ZemlinDivision of Chemical Pathology, Faculty of Medicine and Health Sciences, Tygerberg Hospital Stellenbosch University and National Health Laboratory Service (NHLS) Cape Town Western Cape South Africa.
Thumeka JalavuDivision of Chemical Pathology, Faculty of Medicine and Health Sciences, Tygerberg Hospital Stellenbosch University and National Health Laboratory Service (NHLS) Cape Town Western Cape South Africa.
Nomusa MashigoDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
Carissa ChettyDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
Nokwazi NkosiDivision of Virology, Faculty of Medicine and Health Sciences, Tygerberg Hospital Stellenbosch University and National Health Laboratory Service (NHLS) Cape Town Western Cape South Africa.
Zivanai C ChapandukaDivision of Haematological Pathology, Faculty of Medicine and Health Sciences Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg Hospital Cape Town Western Cape Province South Africa.
National Health Laboratory Service · ZATygerberg Hospital · ZAStellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coronavirus disease 2019 (COVID-19) is associated with hematological abnormalities of variable severity. The full blood count (FBC) and leukocyte differential count (DIFF) could facilitate the prediction of disease severity and outcome in COVID-19. This study aimed to assess the hematological parameters in early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and their correlation with disease outcome. Methods: A retrospective cross-sectional descriptive study was performed. Adults with a FBC and positive SARS-CoV-2 polymerase chain reaction results between March 1, and June 31, 2020 were reviewed. Basic hematological parameters (FBC, DIFF) and human immunodeficiency virus (HIV) status were recorded. Outcome measures were admission to a general ward or intensive care unit (ICU), recovery or death. Results: Six hundred and eighty-five cases median age 51 years, were analyzed. Forty-four percent were males and fourteen percent were HIV-positive with no association between death and/or ICU admission ( Conclusion: Evidence-based interpretation of routine laboratory parameters, readily available in resource-constrained settings, may identify patients at increased risk of mortality. The FBC, DIFF, NLR, and MLR should form part of the early COVID-19 investigation.

Indexed as

COVID‐19d‐dimerHIVleucocytosisneutrophil‐lymphocyte‐ratioSARS‐CoV‐2

Identifiers

PMID35509400
PMCPMC9059219
OpenAlexW4223989217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.