ReviewHealth science reports2022
Neutrophil-lymphocyte ratio as a predictor of adverse outcome in patients with community-acquired pneumonia: A systematic review.
Review in Health science reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Utility of pneumonia severity assessment tools for mortality prediction in healthcare-associated pneumonia: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Association of complete blood count parameters with adverse outcomes in acute pediatric pneumonia.Pediatric research · 2026Article
- Predictors of secondary cardiovascular events in older adults with community-acquired pneumonia: a prospective observational study.Clinics (Sao Paulo, Brazil) · 2026Article
- Clinical Features and Predictive Risk Factors for Prognosis in Invasive Pulmonary Aspergillosis and Pulmonary Mucormycosis.The clinical respiratory journal · 2026Article
- Neutrophil-to-Lymphocyte Ratio and Systemic Inflammatory Response Index as Predictors of In-Hospital Mortality in Ventilator-Associated Pneumonia Patients.Infection and drug resistance · 2026Article
- Biomarker-concordant Steroid use in Hospitalized Patients with Community-acquired Pneumonia: A Prospective Cohort Study.The open respiratory medicine journal · 2026Article
- Predictive value of neutrophil-to-lymphocyte ratio on hospital outcomes of patients with community-acquired pneumonia.PloS one · 2026Observational
- IMPACT OF LEUKOCYTE INFLAMMATORY MARKERS ON OUTCOMES OF CRITICALLY ILL PATIENTS WITH GASTROINTESTINAL DISEASES.Arquivos de gastroenterologia · 2026Article
- Evaluation of factors affecting Pneumonia Severity Index and antibiotic resistance status in culture-proven bacterial pneumonia.Frontiers in medicine · 2026Article
- Development and validation of a nomogram integrating inflammatory-nutritional-metabolic composite indices for predicting short-term adverse outcomes in hospitalized patients with pneumonia.Frontiers in medicine · 2026Article
- Article
- Role of Systemic Inflammatory Markers in the Differential Diagnosis of Organizing Pneumonia and Lung Cancer.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
- Review
- Differential Analysis of Hemogram Parameters and Cellular Ratios in Severe Asthma Exacerbations: A Comparative Study of Eosinophilic and Non-Eosinophilic Phenotypes.Life (Basel, Switzerland) · 2025Article
- Article
- Predictive Significance of Admission-Day Blood Routine-Derived Indices for 30-Day Mortality Risk in Elderly Patients with Bacterial Pneumonia.International journal of general medicine · 2025Article
- Diagnostic and prognostic utility of salivary and serum procalcitonin, interleukin-6, and interleukin-10 in pediatric pneumonia: a prospective case-control study.Frontiers in pediatrics · 2025Article
- Prognostic value of the platelet, neutrophil, monocyte, basophil, and eosinophil to lymphocyte ratios in patients with severe community-acquired pneumonia (SCAP).Scientific reports · 2024Article
- Association between prognostic nutritional index and mortality risk in patients with community-acquired pneumonia: a retrospective study.BMC pulmonary medicine · 2024Article
- Enhancing pneumonia prognosis in the emergency department: a novel machine learning approach using complete blood count and differential leukocyte count combined with CURB-65 score.BMC medical informatics and decision making · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Community-acquired pneumonia (CAP) is the acute infection of lung tissue in an immunocompetent who acquired it from the community. Its incidence and mortality are significant and require a marker to predict the severity and mortality in these patients. Neutrophil-lymphocyte ratio (NLR) is a simple, cheap, and easy-to-use marker and this study describes its role in predicting the adverse outcome in patients with CAP. Methods: PubMed, EMBASE, and Google Scholar were used to search for related studies on February 8, 2021. A total of 186 articles were retrieved upon detailed searching in the databases and search engines. After a series of removing duplicate articles, title and abstract screening, and full-text review; nine articles were found eligible and included in the study. The data from each article were collected in MS Excel and the findings were summarized in this manuscript. Results: The total number of patients analyzed in this systematic review is 3340. The mean age of the patient in the included studies ranged from 61 to 90.4 years. All studies had adverse outcomes as the endpoint of the study, which included in-hospital mortality or intensive care unit (ICU) admission or deterioration from medium and low risk to high risk or 30 days' mortality. The prevalence of endpoint ranged from 5.8% to 44.8%. NLR with a cutoff value of more than 10 was shown to predict mortality compared to C-reactive protein levels, white blood cell count, neutrophil count, lymphocyte level, Pneumonia Severity Index (PSI) level, PSI class, procalcitonin, and CURB-65 (Confusion, Respiratory rate, Blood pressure, 65 years of age and older) in most of the studies. Conclusion: NLR is a simple, easily measured yet promising marker for predicting outcomes in patients with CAP.
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