ArticleTurkish journal of pharmaceutical sciences2022
Formulation and Development of Aqueous Film Coating for Moisture Protection of Hygroscopic
Article in Turkish journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Investigation of the Photoprotective Effects of Various Pigments Against Laser-Marking of Pharmaceutical Tablets.Pharmaceutics · 2026Article
- Laser-Based QR Code Marking on Double Film-Coated Tablets: Balancing Marking Efficiency and Tablet Integrity-A Step Toward Safer Medicines.Pharmaceutics · 2026Article
- Protection of Hygroscopic Pharmaceutical and Nutraceutical Active Ingredients via Film Coating Technologies: A Review.Drug design, development and therapy · 2026Review
- The Ubiquitous Use of Polyethylene Glycol in Pharmaceutical Design and Development: Technological Aspects and Future Perspectives.Nanomaterials (Basel, Switzerland) · 2025Review
- Antistunting potential of deepsea water concentrate as multivitamin granules: stability and in vivo activity study.Scientific reports · 2025Article
- Formulation Strategies to Improve the Stability and Handling of Oral Solid Dosage Forms of Highly Hygroscopic Pharmaceuticals and Nutraceuticals.Pharmaceutics · 2022Review
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Authors and funding
2 authors.
Funding
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Abstract
Objectives: The present study aims to develop a moisture-protective coating solution and use it to film coat hygroscopic Materials and Methods: Five coating formulations were developed and applied on Results: The results of this study showed that the film coating F5 containing 25% hydroxypropyl methyl cellulose (HPMC), 20% shellac, 10% polyethylene glycol (PEG) 1500, 29.6% PEG 4000, 5% tween 80, 10% titanium dioxide, and 0.4% acid red 2 offered good protection for coated tablets against moisture. Coated tablets showed physical and dissolution stability during storage. Conclusion: A combination of hydrophilic polymer HPMC and hydrophobic polymer shellac is suitable for balancing moisture-protective properties and attaining the fast release of drugs. This study could make it worthwhile to develop a pharmaceutical moisture barrier film coating system for immediate release tablets. However, more studies will be needed to evaluate the moisture-resistant film further.
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Registered trials
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