ArticleBMC musculoskeletal disorders2022
Prevalence of preoperative Deep Venous Thrombosis (DVT) following elderly intertrochanteric fractures and development of a risk prediction model.
Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- The risk prediction models for deep venous thrombosis in perioperative patients with lower limb fractures: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- The impact of frailty evaluation on the risk of venous thromboembolism in patients with hip fracture following surgery: a meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Construction and validation of a nomogram model incorporating the systemic immune-inflammation index for preoperative deep vein thrombosis risk in patients with traumatic lower limb fractures.BMC musculoskeletal disorders · 2026Article
- A machine learning-based risk prediction model for Hospitalized patients with deep vein thrombosis.PeerJ · 2026Article
- Article
- Risk Factors and Prediction Model for Preoperative Lower-Extremity Venous Thrombosis in Elderly Women Undergoing Colpocleisis.International urogynecology journal · 2025Article
- Early Deep Venous Thrombosis After Hip Fracture Surgery in Patients in Pharmacological Prophylaxis.Journal of clinical medicine · 2025Article
- Prediction model of deep vein thrombosis risk after lower extremity orthopedic surgery.Heliyon · 2024Article
- Correlation between ABO blood type and lower extremity deep vein thrombosis in elderly patients following hip fracture.American journal of translational research · 2024Article
- Construction and validation of a clinical prediction model for deep vein thrombosis in patients with digestive system tumors based on a machine learning.American journal of cancer research · 2024Article
- Development and validation of a nomogram for predicting the risk of immediate postoperative deep vein thrombosis after open wedge high tibial osteotomy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- The association between admission serum albumin and preoperative deep venous thrombosis in geriatrics hip fracture: a retrospective study of 1819 patients with age ≥ 65 years.BMC musculoskeletal disorders · 2023Article
- Elderly hip fracture patients with isolated calf muscle vein thrombosis are more likely to have suffered an intertrochanteric fracture and be hypertensive.Journal of orthopaedic surgery and research · 2023Article
- Development and validation of a newly developed nomogram for predicting the risk of deep vein thrombosis after surgery for lower limb fractures in elderly patients.Frontiers in surgery · 2023Article
- Analysis of the Risk Factors for Elevated D-Dimer Level After Breast Cancer Surgery: A Multicenter Study Based on Nursing Follow-Up Data.Frontiers in oncology · 2022Article
- Optimizing Preoperative Venous Thromboembolism Risk Assessment in Elderly Hip Fracture Patients: A Refined Caprini Model Integrating D-Dimer and Injury-to-Admission Time.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Preoperative Venous Thromboembolism in Elderly Patients with Hip Fractures: Independent Risk Factors and Interactions Between D-Dimer and Clinical Variables.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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8 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundThis study aimed to investigate the prevalence of preoperative deep venous thrombosis (DVT) following intertrochanteric fractures in the elderly and identify the associated factors, based on which a risk prediction model was developed.
methodThis was a retrospective single-center study of elderly patients presenting with intertrochanteric fractures between our institution between January 2017 and December 2020. Patients' duplex ultrasound (DUS) or venography results were retrieved to evaluate whether they had a preoperative deep venous thrombosis (DVT) of bilateral extremities, whereby patients were dichotomized. Various variables of interest on demographics, comorbidities, injury and biomarkers were extracted and their relationship between DVT were investigated. Statistically significant variables tested in multivariate logistics regression analyses were used to develop a risk prediction model.
resultsThere were 855 patients eligible to be included in this study, and 105 were found to have preoperative DVT, with a prevalence rate of 12.3%. Ten factors were tested as significantly different and 2 marginally significant between DVT and non-DVT groups in the univariate analyses, but only 6 demonstrated the independent effect on DVT occurrence, including history of a VTE event (OR, 4.43; 95%CI, 2.04 to 9.62), time from injury to DVT screening (OR, 1.19; 95%CI, 1.13 to 1.25), BMI (OR, 1.11; 95%CI, 1.04-1.18), peripheral vascular disease (OR, 2.66; 95%CI, 1.10 to 6.40), reduced albumin (2.35; 95%CI, 1.48 to 3.71) and D-Dimer > 1.0 mg/L(OR, 1.90; 95%CI, 1.13 to 3.20). The DVT risk model showed an AUC of 0.780 (95%CI, 0.731 to 0.829), with a sensitivity of 0.667 and a specificity of 0.777.
conclusionDespite without a so high prevalence rate of DVT in a general population with intertrochanteric fracture, particular attention should be paid to those involved in the associated risk factors above. The risk prediction model exhibited the improved specificity, but its validity required further studies to verify.
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